Inhibition of gamma-secretase activity without interfering in Notch signalling decreases inflammatory response in patients with cutaneous leishmaniasis

Cutaneous leishmaniasis (CL) patients present an exacerbated inflammatory response associated with tissue damage and ulcer development. Increasing numbers of patients have exhibited treatment failure, which remains not well understood. We hypothesized that adjuvant anti-inflammatory therapy would be...

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Detalles Bibliográficos
Autores principales: Nascimento, Maurício T., Franca, Mônica, Carvalho, Augusto M., Amorim, Camila F., Peixoto, Fábio, Beiting, Daniel, Scott, Phillip, Carvalho, Edgar M., Carvalho, Lucas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8676695/
https://www.ncbi.nlm.nih.gov/pubmed/34009107
http://dx.doi.org/10.1080/22221751.2021.1932608

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