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The RBS1 domain of Gemin5 is intrinsically unstructured and interacts with RNA through conserved Arg and aromatic residues
Gemin5 is a multifaceted RNA-binding protein that comprises distinct structural domains, including a WD40 and TPR-like for which the X-ray structure is known. In addition, the protein contains a non-canonical RNA-binding domain (RBS1) towards the C-terminus. To understand the RNA binding features of...
Autores principales: | Embarc-Buh, Azman, Francisco-Velilla, Rosario, Camero, Sergio, Pérez-Cañadillas, José Manuel, Martínez-Salas, Encarnación |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677033/ https://www.ncbi.nlm.nih.gov/pubmed/34424823 http://dx.doi.org/10.1080/15476286.2021.1962666 |
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