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The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study

OBJECTIVES: To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress. METHODS: 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control group was fed w...

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Autores principales: Chien, Kai-Ting, Chen, Ching-Chen, Chu, Chien-Ming, Chan, Ya-Lin, Chung, Hsiu-Yun, Chang, Ting-Kuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677394/
https://www.ncbi.nlm.nih.gov/pubmed/34925548
http://dx.doi.org/10.1155/2021/9934107
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author Chien, Kai-Ting
Chen, Ching-Chen
Chu, Chien-Ming
Chan, Ya-Lin
Chung, Hsiu-Yun
Chang, Ting-Kuo
author_facet Chien, Kai-Ting
Chen, Ching-Chen
Chu, Chien-Ming
Chan, Ya-Lin
Chung, Hsiu-Yun
Chang, Ting-Kuo
author_sort Chien, Kai-Ting
collection PubMed
description OBJECTIVES: To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress. METHODS: 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control group was fed with ordinary drinking water, while the experimental group was fed with CircuCare at a daily dose of 93.75 mg per 300 g of body weight over eight weeks. Both groups were subjected to a swimming test, and blood samples were taken to observe any variations in various biochemical parameters before and after the test. Key Findings. The experimental group's mean swimming exhaustion duration was 53.2% longer and had a significantly higher lactic acid removal ratio. Their mean prostaglandin E2 level and mean glucose, cortisol, and glutathione level (30 minutes after swimming test) were also significantly higher. No undesirable impacts from CircuCare relating to general blood biochemistry values and bone mineral density were reported. CONCLUSIONS: The present results show that CircuCare can be safely used to increase stamina and exercise capability, expedite the metabolism of lactic acid, accelerate muscle repair, and promote the antioxidant activity of cells in rats.
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spelling pubmed-86773942021-12-17 The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study Chien, Kai-Ting Chen, Ching-Chen Chu, Chien-Ming Chan, Ya-Lin Chung, Hsiu-Yun Chang, Ting-Kuo Comput Math Methods Med Research Article OBJECTIVES: To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress. METHODS: 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control group was fed with ordinary drinking water, while the experimental group was fed with CircuCare at a daily dose of 93.75 mg per 300 g of body weight over eight weeks. Both groups were subjected to a swimming test, and blood samples were taken to observe any variations in various biochemical parameters before and after the test. Key Findings. The experimental group's mean swimming exhaustion duration was 53.2% longer and had a significantly higher lactic acid removal ratio. Their mean prostaglandin E2 level and mean glucose, cortisol, and glutathione level (30 minutes after swimming test) were also significantly higher. No undesirable impacts from CircuCare relating to general blood biochemistry values and bone mineral density were reported. CONCLUSIONS: The present results show that CircuCare can be safely used to increase stamina and exercise capability, expedite the metabolism of lactic acid, accelerate muscle repair, and promote the antioxidant activity of cells in rats. Hindawi 2021-12-02 /pmc/articles/PMC8677394/ /pubmed/34925548 http://dx.doi.org/10.1155/2021/9934107 Text en Copyright © 2021 Kai-Ting Chien et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chien, Kai-Ting
Chen, Ching-Chen
Chu, Chien-Ming
Chan, Ya-Lin
Chung, Hsiu-Yun
Chang, Ting-Kuo
The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study
title The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study
title_full The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study
title_fullStr The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study
title_full_unstemmed The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study
title_short The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study
title_sort determination of efficacy of circucare on blood circulation and metabolism: an animal model study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677394/
https://www.ncbi.nlm.nih.gov/pubmed/34925548
http://dx.doi.org/10.1155/2021/9934107
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