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Dopamine-dependent early synaptic and motor dysfunctions induced by α-synuclein in the nigrostriatal circuit
Misfolding and aggregation of α-synuclein are specific features of Parkinson’s disease and other neurodegenerative diseases defined as synucleinopathies. Parkinson’s disease progression has been correlated with the formation and extracellular release of α-synuclein aggregates, as well as with their...
Autores principales: | Tozzi, Alessandro, Sciaccaluga, Miriam, Loffredo, Vittorio, Megaro, Alfredo, Ledonne, Ada, Cardinale, Antonella, Federici, Mauro, Bellingacci, Laura, Paciotti, Silvia, Ferrari, Elena, La Rocca, Antonino, Martini, Alessandro, Mercuri, Nicola B, Gardoni, Fabrizio, Picconi, Barbara, Ghiglieri, Veronica, De Leonibus, Elvira, Calabresi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677552/ https://www.ncbi.nlm.nih.gov/pubmed/34297092 http://dx.doi.org/10.1093/brain/awab242 |
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