Genetic analysis of four consanguineous multiplex families with inflammatory bowel disease

BACKGROUND: Family studies support a genetic predisposition to inflammatory bowel diseases (IBD), but known genetic variants only partially explain the disease heritability. Families with multiple affected individuals potentially harbour rare and high-impact causal variants. Long regions of homozygo...

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Detalles Bibliográficos
Autores principales: Ben-Yosef, Noam, Frampton, Matthew, Schiff, Elena R, Daher, Saleh, Abu Baker, Fadi, Safadi, Rifaat, Israeli, Eran, Segal, Anthony W, Levine, Adam P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677555/
https://www.ncbi.nlm.nih.gov/pubmed/34925849
http://dx.doi.org/10.1093/gastro/goab007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677555/
https://www.ncbi.nlm.nih.gov/pubmed/34925849
http://dx.doi.org/10.1093/gastro/goab007

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