Cargando…

Adoptive Cell Transfer of Allogeneic Epstein–Barr Virus-Specific T Lymphocytes for Treatment of Refractory EBV-Associated Posttransplant Smooth Muscle Tumors: A Case Report

Posttransplant smooth muscle tumors (PTSMTs) are rare Epstein–Barr virus (EBV)-associated neoplasms, mostly occurring after solid organ transplantation. Current therapeutic strategies include surgery and reduction of immunosuppressive medication. We describe for the first time a novel treatment appr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hansen, Bjoern-Thore, Bacher, Petra, Eiz-Vesper, Britta, Heckl, Steffen M., Klapper, Wolfram, Koch, Karoline, Maecker-Kolhoff, Britta, Baldus, Claudia D., Fransecky, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677671/ https://www.ncbi.nlm.nih.gov/pubmed/34925312 http://dx.doi.org/10.3389/fimmu.2021.727814

Ejemplares similares

Refractory Epstein-Barr Virus (EBV)-Related Post-transplant Lymphoproliferative Disease: Cure by Combined Brentuximab Vedotin and Allogeneic EBV-Specific T-Lymphocytes
por: Mika, Thomas, et al.
Publicado: (2019)

Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease
por: Schultze-Florey, Rebecca E., et al.
Publicado: (2018)

Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes
por: Bieling, Maren, et al.
Publicado: (2017)

Reinforcement of cell-mediated immunity driven by tumor-associated Epstein-Barr virus (EBV)-specific T cells during targeted B-cell therapy with rituximab
por: Tischer-Zimmermann, Sabine, et al.
Publicado: (2023)

Adoptive T-cell immunotherapy from third-party donors: characterization of donors and set up of a T-cell donor registry
por: Eiz-Vesper, Britta, et al.
Publicado: (2013)

High-intensity interval training in allogeneic adoptive T-cell immunotherapy – a big HIT?
por: Heinemann, Nele Carolin, et al.
Publicado: (2020)

Posttransplant Lymphoproliferative Disease after Pediatric Solid Organ Transplantation
por: Mynarek, Martin, et al.
Publicado: (2013)

Long-Term Follow-Up after Adoptive Transfer of BK-Virus-Specific T Cells in Hematopoietic Stem Cell Transplant Recipients
por: Koldehoff, Michael, et al.
Publicado: (2023)

Combined Treatment With Pembrolizumab and Allogenic BK Virus-Specific T Cells in Progressive Multifocal Leukoencephalopathy: A Case Report
por: Wicklein, Rebecca, et al.
Publicado: (2021)

Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies
por: Tischer, Sabine, et al.
Publicado: (2011)

Adoptive Allogeneic T-Cell Therapy Improves the Clinical Outcome of JC Virus Granule Cell Neuronopathy: A Case Report
por: Grote-Levi, Lea, et al.
Publicado: (2023)

CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation
por: Dragon, Anna Christina, et al.
Publicado: (2020)

Allogeneic BK Virus-Specific T-Cell Treatment in 2 Patients With Progressive Multifocal Leukoencephalopathy
por: Hopfner, Franziska, et al.
Publicado: (2021)

Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection
por: Tischer, Sabine, et al.
Publicado: (2016)

MicroRNA expression in Epstein-Barr virus-associated post-transplant smooth muscle tumours is related to leiomyomatous phenotype
por: Jonigk, Danny, et al.
Publicado: (2013)

Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads
por: Mangare, Caroline, et al.
Publicado: (2019)

Innovative therapeutic concepts of progressive multifocal leukoencephalopathy
por: Möhn, Nora, et al.
Publicado: (2022)

Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression
por: Bak, Szilvia, et al.
Publicado: (2018)

Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy
por: Schillingmann, Damaris A., et al.
Publicado: (2019)

Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors
por: Bonifacius, Agnes, et al.
Publicado: (2023)

Stem Cell Therapy in Neuroimmunological Diseases and Its Potential Neuroimmunological Complications
por: Konen, Franz Felix, et al.
Publicado: (2022)

Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells
por: Tischer, Sabine, et al.
Publicado: (2014)

Comparative Analysis of Clinical-Scale IFN-γ-Positive T-Cell Enrichment Using Partially and Fully Integrated Platforms
por: Priesner, Christoph, et al.
Publicado: (2016)

Epstein-Barr virus associated posttransplant malignant lymphoma in renal allograft recipients.
por: Choi, Y. J., et al.
Publicado: (1994)

Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
por: Torti, Lorenza, et al.
Publicado: (2012)

Epstein-Barr Virus (EBV)-associated Gastric Carcinoma
por: Iizasa, Hisashi, et al.
Publicado: (2012)

Epstein–Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV
por: Venturini, Cristina, et al.
Publicado: (2021)

Rapid and sustained T cell-based immunotherapy against invasive fungal disease via a combined two step procedure
por: Tischer-Zimmermann, Sabine, et al.
Publicado: (2023)

Opportunities to Target the Life Cycle of Epstein-Barr Virus (EBV) in EBV-Associated Lymphoproliferative Disorders
por: Dugan, James P., et al.
Publicado: (2019)

Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor
por: Bunse, Carola E., et al.
Publicado: (2013)

Establishment and operation of a Good Manufacturing Practice-compliant allogeneic Epstein-Barr virus (EBV)-specific cytotoxic cell bank for the treatment of EBV-associated lymphoproliferative disease
por: Vickers, Mark A, et al.
Publicado: (2014)

Antiviral T-Cell Frequencies in a Healthy Population: Reference Values for Evaluating Antiviral Immune Cell Profiles in Immunocompromised Patients
por: Schulze Lammers, Friederike C., et al.
Publicado: (2022)

Epstein-Barr virus (EBV)-associated miRNAs are important for the maintenance of EBV transformed B cells
por: Linnstaedt, Sarah, et al.
Publicado: (2010)

Epstein–Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact
por: Carpén, Timo, et al.
Publicado: (2020)

Updates on Epstein–Barr Virus (EBV)-Associated Nasopharyngeal Carcinoma: Emphasis on the Latent Gene Products of EBV
por: Ahmed, Naveed, et al.
Publicado: (2022)

Pathogenic Role of Exosomes in Epstein-Barr Virus (EBV)-Associated Cancers
por: Teow, Sin-Yeang, et al.
Publicado: (2017)

Molecular Epidemiology of Epstein-Barr virus (EBV) in Patients with Hematologic Malignancies
por: Tabibzadeh, Alireza, et al.
Publicado: (2020)

Prevalence of Epstein–Barr virus (EBV) in Iranian Breast Carcinoma Patients
por: Golrokh Mofrad, Morvarid, et al.
Publicado: (2020)

An Acute Presentation of Epstein-Barr Virus (EBV) Infection in an Immunocompromised Gentleman
por: Bhattacharjee, Shaumick, et al.
Publicado: (2022)

Association of Epstein-Barr virus (EBV) with lung cancer: meta-analysis
por: Chen, Yizhuo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lb2itrlrbpgo96gq6er1vsk2nu