An RNA–RNA crosstalk network involving HMGB1 and RICTOR facilitates hepatocellular carcinoma tumorigenesis by promoting glutamine metabolism and impedes immunotherapy by PD-L1+ exosomes activity

Hepatocellular carcinoma (HCC) is the global leading cause of cancer-related deaths due to the deficiency of targets for precision therapy. A new modality of epigenetic regulation has emerged involving RNA–RNA crosstalk networks where two or more competing endogenous RNAs (ceRNAs) bind to the same m...

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Detalles Bibliográficos
Autores principales: Wei, Yanping, Tang, Xuewu, Ren, Yibin, Yang, Yun, Song, Fengliang, Fu, Jingbo, Liu, Shuowu, Yu, Miao, Chen, Jing, Wang, Suyang, Zhang, Kecheng, Tan, Yexiong, Han, Zhipeng, Wei, Lixin, Zhang, Baohua, Cheng, Zhangjun, Li, Liang, Wang, Hongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677721/
https://www.ncbi.nlm.nih.gov/pubmed/34916485
http://dx.doi.org/10.1038/s41392-021-00801-2

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