Detachable dissolvable microneedles: intra-epidermal and intradermal diffusion, effect on skin surface, and application in hyperpigmentation treatment

Delivering bioactive compounds into skin tissue has long been a challenge. Using ex vivo porcine and rat skins, here we demonstrate that a detachable dissolvable microneedle (DDMN) array, a special dissolvable microneedle that allows needle detachment from the base within 2 min post administration,...

Descripción completa

Detalles Bibliográficos
Autores principales: Sawutdeechaikul, Pritsana, Kanokrungsee, Silada, Sahaspot, Thanyapat, Thadvibun, Kamonwan, Banlunara, Wijit, Limcharoen, Benchaphorn, Sansureerungsikul, Titiporn, Rutwaree, Teeranut, Oungeun, Miranda, Wanichwecharungruang, Supason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677736/
https://www.ncbi.nlm.nih.gov/pubmed/34916571
http://dx.doi.org/10.1038/s41598-021-03503-5

Ejemplares similares

Ejemplares similares