Comprehensive exploration of chemical space using trisubstituted carboranes

A total of 42 trisubstituted carboranes categorised into five scaffolds were systematically designed and synthesized by exploiting the different reactivities of the twelve vertices of o-, m-, and p-carboranes to cover all directions in chemical space. Significant inhibitors of hypoxia inducible fact...

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Detalles Bibliográficos
Autores principales: Asawa, Yasunobu, Hatsuzawa, Saki, Yoshimori, Atsushi, Yamada, Kentaro, Katoh, Akira, Kouji, Hiroyuki, Nakamura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677773/
https://www.ncbi.nlm.nih.gov/pubmed/34916538
http://dx.doi.org/10.1038/s41598-021-03459-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677773/
https://www.ncbi.nlm.nih.gov/pubmed/34916538
http://dx.doi.org/10.1038/s41598-021-03459-6

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