Recommended tool compounds and drugs for blocking P2X and P2Y receptors

This review article presents a collection of tool compounds that selectively block and are recommended for studying P2Y and P2X receptor subtypes, investigating their roles in physiology and validating them as future drug targets. Moreover, drug candidates and approved drugs for P2 receptors will be...

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Detalles Bibliográficos
Autores principales: Müller, Christa E., Namasivayam, Vigneshwaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677864/
https://www.ncbi.nlm.nih.gov/pubmed/34476721
http://dx.doi.org/10.1007/s11302-021-09813-7
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author Müller, Christa E.
Namasivayam, Vigneshwaran
author_facet Müller, Christa E.
Namasivayam, Vigneshwaran
author_sort Müller, Christa E.
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description This review article presents a collection of tool compounds that selectively block and are recommended for studying P2Y and P2X receptor subtypes, investigating their roles in physiology and validating them as future drug targets. Moreover, drug candidates and approved drugs for P2 receptors will be discussed.
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spelling pubmed-86778642021-12-22 Recommended tool compounds and drugs for blocking P2X and P2Y receptors Müller, Christa E. Namasivayam, Vigneshwaran Purinergic Signal Review Article This review article presents a collection of tool compounds that selectively block and are recommended for studying P2Y and P2X receptor subtypes, investigating their roles in physiology and validating them as future drug targets. Moreover, drug candidates and approved drugs for P2 receptors will be discussed. Springer Netherlands 2021-09-02 2021-12 /pmc/articles/PMC8677864/ /pubmed/34476721 http://dx.doi.org/10.1007/s11302-021-09813-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Müller, Christa E.
Namasivayam, Vigneshwaran
Recommended tool compounds and drugs for blocking P2X and P2Y receptors
title Recommended tool compounds and drugs for blocking P2X and P2Y receptors
title_full Recommended tool compounds and drugs for blocking P2X and P2Y receptors
title_fullStr Recommended tool compounds and drugs for blocking P2X and P2Y receptors
title_full_unstemmed Recommended tool compounds and drugs for blocking P2X and P2Y receptors
title_short Recommended tool compounds and drugs for blocking P2X and P2Y receptors
title_sort recommended tool compounds and drugs for blocking p2x and p2y receptors
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677864/
https://www.ncbi.nlm.nih.gov/pubmed/34476721
http://dx.doi.org/10.1007/s11302-021-09813-7
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