Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report

TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling.

Detalles Bibliográficos
Autores principales: Sato, Hiroshi, Matsuo, Seiki, Ando, Yukiko, Imamura, Yuko, Hirose, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677884/
https://www.ncbi.nlm.nih.gov/pubmed/34963807
http://dx.doi.org/10.1002/ccr3.5221
Descripción
Sumario:TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling.

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