Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report

TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling.

Detalles Bibliográficos
Autores principales: Sato, Hiroshi, Matsuo, Seiki, Ando, Yukiko, Imamura, Yuko, Hirose, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677884/
https://www.ncbi.nlm.nih.gov/pubmed/34963807
http://dx.doi.org/10.1002/ccr3.5221
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author Sato, Hiroshi
Matsuo, Seiki
Ando, Yukiko
Imamura, Yuko
Hirose, Masaya
author_facet Sato, Hiroshi
Matsuo, Seiki
Ando, Yukiko
Imamura, Yuko
Hirose, Masaya
author_sort Sato, Hiroshi
collection PubMed
description TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling.
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spelling pubmed-86778842021-12-27 Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report Sato, Hiroshi Matsuo, Seiki Ando, Yukiko Imamura, Yuko Hirose, Masaya Clin Case Rep Case Report TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling. John Wiley and Sons Inc. 2021-12-16 /pmc/articles/PMC8677884/ /pubmed/34963807 http://dx.doi.org/10.1002/ccr3.5221 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Sato, Hiroshi
Matsuo, Seiki
Ando, Yukiko
Imamura, Yuko
Hirose, Masaya
Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report
title Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report
title_full Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report
title_fullStr Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report
title_full_unstemmed Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report
title_short Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report
title_sort germline tp53 c.566c>t mutation incidentally diagnosed during treatment for acute myeloid leukemia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677884/
https://www.ncbi.nlm.nih.gov/pubmed/34963807
http://dx.doi.org/10.1002/ccr3.5221
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