Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma

The standardized treatment plan for patients with plasmablastic lymphoma (PBL) remains controversial. Taking morphological characteristics and immunophenotypes into consideration may provide superior options for the treatment of PBL. In this case, we report that a myeloma-type regimen containing bor...

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Detalles Bibliográficos
Autores principales: Cai, Jiao, Qiu, Ling, Ma, Lei, Zhang, Nan, Fan, Fang-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677941/
https://www.ncbi.nlm.nih.gov/pubmed/34926499
http://dx.doi.org/10.3389/fmed.2021.749863
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author Cai, Jiao
Qiu, Ling
Ma, Lei
Zhang, Nan
Fan, Fang-yi
author_facet Cai, Jiao
Qiu, Ling
Ma, Lei
Zhang, Nan
Fan, Fang-yi
author_sort Cai, Jiao
collection PubMed
description The standardized treatment plan for patients with plasmablastic lymphoma (PBL) remains controversial. Taking morphological characteristics and immunophenotypes into consideration may provide superior options for the treatment of PBL. In this case, we report that a myeloma-type regimen containing bortezomib plus cyclophosphamide, epirubicin, vindesine and prednisolone (CDOP) followed by sequential autologous hematopoietic stem cell transplantation (ASCT) and lenalidomide-based maintenance therapy to treat PBL may represent a promising regimen to improve the prognosis.
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spelling pubmed-86779412021-12-18 Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma Cai, Jiao Qiu, Ling Ma, Lei Zhang, Nan Fan, Fang-yi Front Med (Lausanne) Medicine The standardized treatment plan for patients with plasmablastic lymphoma (PBL) remains controversial. Taking morphological characteristics and immunophenotypes into consideration may provide superior options for the treatment of PBL. In this case, we report that a myeloma-type regimen containing bortezomib plus cyclophosphamide, epirubicin, vindesine and prednisolone (CDOP) followed by sequential autologous hematopoietic stem cell transplantation (ASCT) and lenalidomide-based maintenance therapy to treat PBL may represent a promising regimen to improve the prognosis. Frontiers Media S.A. 2021-12-03 /pmc/articles/PMC8677941/ /pubmed/34926499 http://dx.doi.org/10.3389/fmed.2021.749863 Text en Copyright © 2021 Cai, Qiu, Ma, Zhang and Fan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Cai, Jiao
Qiu, Ling
Ma, Lei
Zhang, Nan
Fan, Fang-yi
Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_full Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_fullStr Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_full_unstemmed Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_short Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_sort case report: bortezomib plus cdop followed by sequential autologous hematopoietic stem cell transplantation and lenalidomide-based maintenance therapy in plasmablastic lymphoma
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677941/
https://www.ncbi.nlm.nih.gov/pubmed/34926499
http://dx.doi.org/10.3389/fmed.2021.749863
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