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The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report

RATIONALE: Using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), we demonstrated blood-brain barrier (BBB) disruption following syncope. PATIENT CONCERNS: A 45-year-old man experienced syncope with a chief complaint of syncope (duration: 1 minutes), 1 day before visiting a university...

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Autores principales: Huh, Hyungkyu, Lee, Eun-Hee, Oh, Sung Suk, Kim, Jong-Hoon, Seo, Young Beom, Choo, Yoo Jin, Park, Juyoung, Chang, Min Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677986/
https://www.ncbi.nlm.nih.gov/pubmed/34918695
http://dx.doi.org/10.1097/MD.0000000000028258
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author Huh, Hyungkyu
Lee, Eun-Hee
Oh, Sung Suk
Kim, Jong-Hoon
Seo, Young Beom
Choo, Yoo Jin
Park, Juyoung
Chang, Min Cheol
author_facet Huh, Hyungkyu
Lee, Eun-Hee
Oh, Sung Suk
Kim, Jong-Hoon
Seo, Young Beom
Choo, Yoo Jin
Park, Juyoung
Chang, Min Cheol
author_sort Huh, Hyungkyu
collection PubMed
description RATIONALE: Using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), we demonstrated blood-brain barrier (BBB) disruption following syncope. PATIENT CONCERNS: A 45-year-old man experienced syncope with a chief complaint of syncope (duration: 1 minutes), 1 day before visiting a university hospital for examination. He had no history of medical problems and was not taking any medications. This episode was the first in his lifetime. DIAGNOSES: After syncope, the patient did not have any illnesses or symptoms, such as headache, cognitive deficits, or somnolence. INTERVENTIONS: Cardiac evaluation did not reveal any abnormal findings. In addition, in conventional brain and chest computed tomography and brain MRI, no abnormal lesions were observed. OUTCOMES: DCE-MRI of the patient showed bright blue colored lines within the sulci throughout the cerebral cortex. The regions of interest, including bright blue colored lines, had significantly higher K(trans) values (6.86 times higher) than those in healthy control participants. These findings are indicative of BBB disruption of the vessels in the sulci. LESSONS: Using DCE-MRI, we demonstrated BBB disruption following syncope. DCE-MRI is a useful tool for the detection of BBB disruption following syncope.
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spelling pubmed-86779862021-12-20 The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report Huh, Hyungkyu Lee, Eun-Hee Oh, Sung Suk Kim, Jong-Hoon Seo, Young Beom Choo, Yoo Jin Park, Juyoung Chang, Min Cheol Medicine (Baltimore) 5300 RATIONALE: Using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), we demonstrated blood-brain barrier (BBB) disruption following syncope. PATIENT CONCERNS: A 45-year-old man experienced syncope with a chief complaint of syncope (duration: 1 minutes), 1 day before visiting a university hospital for examination. He had no history of medical problems and was not taking any medications. This episode was the first in his lifetime. DIAGNOSES: After syncope, the patient did not have any illnesses or symptoms, such as headache, cognitive deficits, or somnolence. INTERVENTIONS: Cardiac evaluation did not reveal any abnormal findings. In addition, in conventional brain and chest computed tomography and brain MRI, no abnormal lesions were observed. OUTCOMES: DCE-MRI of the patient showed bright blue colored lines within the sulci throughout the cerebral cortex. The regions of interest, including bright blue colored lines, had significantly higher K(trans) values (6.86 times higher) than those in healthy control participants. These findings are indicative of BBB disruption of the vessels in the sulci. LESSONS: Using DCE-MRI, we demonstrated BBB disruption following syncope. DCE-MRI is a useful tool for the detection of BBB disruption following syncope. Lippincott Williams & Wilkins 2021-12-17 /pmc/articles/PMC8677986/ /pubmed/34918695 http://dx.doi.org/10.1097/MD.0000000000028258 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 5300
Huh, Hyungkyu
Lee, Eun-Hee
Oh, Sung Suk
Kim, Jong-Hoon
Seo, Young Beom
Choo, Yoo Jin
Park, Juyoung
Chang, Min Cheol
The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report
title The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report
title_full The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report
title_fullStr The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report
title_full_unstemmed The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report
title_short The blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: A case report
title_sort blood-brain barrier disruption after syncope: a dynamic contrast-enhanced magnetic resonance imaging study: a case report
topic 5300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677986/
https://www.ncbi.nlm.nih.gov/pubmed/34918695
http://dx.doi.org/10.1097/MD.0000000000028258
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