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Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report

RATIONALE: This report describes rehabilitation for a 53-year-old female recovering from non-healing skin and soft tissue defect after distal tibial open fracture by using platelet-rich fibrin topical repair following an automobile accident. PATIENT CONCERNS: The patient was admitted to a rehabilita...

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Autores principales: Lin, Xingzhen, Zhu, Manhua, Yuan, Juan, Zhi, Fang, Hou, XinJu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677990/
https://www.ncbi.nlm.nih.gov/pubmed/34918648
http://dx.doi.org/10.1097/MD.0000000000027994
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author Lin, Xingzhen
Zhu, Manhua
Yuan, Juan
Zhi, Fang
Hou, XinJu
author_facet Lin, Xingzhen
Zhu, Manhua
Yuan, Juan
Zhi, Fang
Hou, XinJu
author_sort Lin, Xingzhen
collection PubMed
description RATIONALE: This report describes rehabilitation for a 53-year-old female recovering from non-healing skin and soft tissue defect after distal tibial open fracture by using platelet-rich fibrin topical repair following an automobile accident. PATIENT CONCERNS: The patient was admitted to a rehabilitation specialty hospital approximately 1 year post a fracture of the distal left tibiofibula and separate surgical tibiofibular fracture incision and internal fixation + bone grafting. DIAGNOSES: Clinical presentation included the left ankle incision was interrupted for about 3 cm with poor healing, a small amount of muscle necrosis, fat liquefaction, a large amount of yellow purulent secretion overflow and necrotic material was seen in the local wound. INTERVENTIONS: Platelet rich fibrin (PRF) gel was injected into the wounds and submerged sites to make full contact with the wounds and close the wounds with the autologous platelet-rich fibrin prepared by mixing, and then covered with oil gauze to keep the wounds moist and promote granulation growth. The outermost layer was covered with cotton pads. OUTCOMES: After 30 days of 2 PRF treatments, the skin defect was healed and no significant abnormality was observed at 6 months follow-up. LESSONS: Treatment with topical autologous platelet-rich plasma gel Significantly accelerates the healing of wounds, shortens healing time, improves healing quality and reduces scar formation without significant adverse effects.
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spelling pubmed-86779902021-12-20 Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report Lin, Xingzhen Zhu, Manhua Yuan, Juan Zhi, Fang Hou, XinJu Medicine (Baltimore) 6600 RATIONALE: This report describes rehabilitation for a 53-year-old female recovering from non-healing skin and soft tissue defect after distal tibial open fracture by using platelet-rich fibrin topical repair following an automobile accident. PATIENT CONCERNS: The patient was admitted to a rehabilitation specialty hospital approximately 1 year post a fracture of the distal left tibiofibula and separate surgical tibiofibular fracture incision and internal fixation + bone grafting. DIAGNOSES: Clinical presentation included the left ankle incision was interrupted for about 3 cm with poor healing, a small amount of muscle necrosis, fat liquefaction, a large amount of yellow purulent secretion overflow and necrotic material was seen in the local wound. INTERVENTIONS: Platelet rich fibrin (PRF) gel was injected into the wounds and submerged sites to make full contact with the wounds and close the wounds with the autologous platelet-rich fibrin prepared by mixing, and then covered with oil gauze to keep the wounds moist and promote granulation growth. The outermost layer was covered with cotton pads. OUTCOMES: After 30 days of 2 PRF treatments, the skin defect was healed and no significant abnormality was observed at 6 months follow-up. LESSONS: Treatment with topical autologous platelet-rich plasma gel Significantly accelerates the healing of wounds, shortens healing time, improves healing quality and reduces scar formation without significant adverse effects. Lippincott Williams & Wilkins 2021-12-17 /pmc/articles/PMC8677990/ /pubmed/34918648 http://dx.doi.org/10.1097/MD.0000000000027994 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 6600
Lin, Xingzhen
Zhu, Manhua
Yuan, Juan
Zhi, Fang
Hou, XinJu
Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report
title Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report
title_full Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report
title_fullStr Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report
title_full_unstemmed Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report
title_short Clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: A case report
title_sort clinical use of platelet-rich fibrin in the repair of non-healing incision wounds after fibular fracture surgery: a case report
topic 6600
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677990/
https://www.ncbi.nlm.nih.gov/pubmed/34918648
http://dx.doi.org/10.1097/MD.0000000000027994
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