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A Deep-Learning Pipeline for TSS Coverage Imputation From Shallow Cell-Free DNA Sequencing
Cell-free DNA (cfDNA) serves as a footprint of the nucleosome occupancy status of transcription start sites (TSSs), and has been subject to wide development for use in noninvasive health monitoring and disease detection. However, the requirement for high sequencing depth limits its clinical use. Her...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678047/ https://www.ncbi.nlm.nih.gov/pubmed/34926480 http://dx.doi.org/10.3389/fmed.2021.684238 |