A Deep-Learning Pipeline for TSS Coverage Imputation From Shallow Cell-Free DNA Sequencing

Cell-free DNA (cfDNA) serves as a footprint of the nucleosome occupancy status of transcription start sites (TSSs), and has been subject to wide development for use in noninvasive health monitoring and disease detection. However, the requirement for high sequencing depth limits its clinical use. Her...

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Detalles Bibliográficos
Autores principales: Han, Bo-Wei, Yang, Xu, Qu, Shou-Fang, Guo, Zhi-Wei, Huang, Li-Min, Li, Kun, Ouyang, Guo-Jun, Cai, Geng-Xi, Xiao, Wei-Wei, Weng, Rong-Tao, Xu, Shun, Huang, Jie, Yang, Xue-Xi, Wu, Ying-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678047/
https://www.ncbi.nlm.nih.gov/pubmed/34926480
http://dx.doi.org/10.3389/fmed.2021.684238

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