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COVID-19 and Obesity: Overlapping of Two Pandemics

BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMM...

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Autores principales: Gammone, Maria Alessandra, D'Orazio, Nicolantonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678214/
https://www.ncbi.nlm.nih.gov/pubmed/34569546
http://dx.doi.org/10.1159/000518386
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author Gammone, Maria Alessandra
D'Orazio, Nicolantonio
author_facet Gammone, Maria Alessandra
D'Orazio, Nicolantonio
author_sort Gammone, Maria Alessandra
collection PubMed
description BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMMARY: Obesity and metabolic disorders are closely linked to chronic systemic inflammation. The adipose tissue constitutes a source of cytokines, which configure a low-grade inflammation and a hypercoagulation status; in addition, diagnosis and care of obese patients are often complicated by excess weight and ventilation difficulties. KEY MESSAGES: This review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related COVID-19 complications.
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spelling pubmed-86782142021-12-17 COVID-19 and Obesity: Overlapping of Two Pandemics Gammone, Maria Alessandra D'Orazio, Nicolantonio Obes Facts Review Article BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMMARY: Obesity and metabolic disorders are closely linked to chronic systemic inflammation. The adipose tissue constitutes a source of cytokines, which configure a low-grade inflammation and a hypercoagulation status; in addition, diagnosis and care of obese patients are often complicated by excess weight and ventilation difficulties. KEY MESSAGES: This review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related COVID-19 complications. S. Karger AG 2021-09-24 /pmc/articles/PMC8678214/ /pubmed/34569546 http://dx.doi.org/10.1159/000518386 Text en Copyright © 2021 by S. Karger AG, Basel
spellingShingle Review Article
Gammone, Maria Alessandra
D'Orazio, Nicolantonio
COVID-19 and Obesity: Overlapping of Two Pandemics
title COVID-19 and Obesity: Overlapping of Two Pandemics
title_full COVID-19 and Obesity: Overlapping of Two Pandemics
title_fullStr COVID-19 and Obesity: Overlapping of Two Pandemics
title_full_unstemmed COVID-19 and Obesity: Overlapping of Two Pandemics
title_short COVID-19 and Obesity: Overlapping of Two Pandemics
title_sort covid-19 and obesity: overlapping of two pandemics
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678214/
https://www.ncbi.nlm.nih.gov/pubmed/34569546
http://dx.doi.org/10.1159/000518386
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