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COVID-19 and Obesity: Overlapping of Two Pandemics
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMM...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678214/ https://www.ncbi.nlm.nih.gov/pubmed/34569546 http://dx.doi.org/10.1159/000518386 |
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author | Gammone, Maria Alessandra D'Orazio, Nicolantonio |
author_facet | Gammone, Maria Alessandra D'Orazio, Nicolantonio |
author_sort | Gammone, Maria Alessandra |
collection | PubMed |
description | BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMMARY: Obesity and metabolic disorders are closely linked to chronic systemic inflammation. The adipose tissue constitutes a source of cytokines, which configure a low-grade inflammation and a hypercoagulation status; in addition, diagnosis and care of obese patients are often complicated by excess weight and ventilation difficulties. KEY MESSAGES: This review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related COVID-19 complications. |
format | Online Article Text |
id | pubmed-8678214 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-86782142021-12-17 COVID-19 and Obesity: Overlapping of Two Pandemics Gammone, Maria Alessandra D'Orazio, Nicolantonio Obes Facts Review Article BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMMARY: Obesity and metabolic disorders are closely linked to chronic systemic inflammation. The adipose tissue constitutes a source of cytokines, which configure a low-grade inflammation and a hypercoagulation status; in addition, diagnosis and care of obese patients are often complicated by excess weight and ventilation difficulties. KEY MESSAGES: This review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related COVID-19 complications. S. Karger AG 2021-09-24 /pmc/articles/PMC8678214/ /pubmed/34569546 http://dx.doi.org/10.1159/000518386 Text en Copyright © 2021 by S. Karger AG, Basel |
spellingShingle | Review Article Gammone, Maria Alessandra D'Orazio, Nicolantonio COVID-19 and Obesity: Overlapping of Two Pandemics |
title | COVID-19 and Obesity: Overlapping of Two Pandemics |
title_full | COVID-19 and Obesity: Overlapping of Two Pandemics |
title_fullStr | COVID-19 and Obesity: Overlapping of Two Pandemics |
title_full_unstemmed | COVID-19 and Obesity: Overlapping of Two Pandemics |
title_short | COVID-19 and Obesity: Overlapping of Two Pandemics |
title_sort | covid-19 and obesity: overlapping of two pandemics |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678214/ https://www.ncbi.nlm.nih.gov/pubmed/34569546 http://dx.doi.org/10.1159/000518386 |
work_keys_str_mv | AT gammonemariaalessandra covid19andobesityoverlappingoftwopandemics AT dorazionicolantonio covid19andobesityoverlappingoftwopandemics |