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Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination

INTRODUCTION: Various skin findings due to coronavirus have been identified. There are a few case reports on nail findings after coronavirus (COVID-19) infection. We aimed to document the nail findings of the COVID-19 survivors and shed light on the interesting luminescence seen under the Wood'...

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Autores principales: Yanatma, Irem, Cenk, Hulya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678237/
https://www.ncbi.nlm.nih.gov/pubmed/34934766
http://dx.doi.org/10.1159/000518983
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author Yanatma, Irem
Cenk, Hulya
author_facet Yanatma, Irem
Cenk, Hulya
author_sort Yanatma, Irem
collection PubMed
description INTRODUCTION: Various skin findings due to coronavirus have been identified. There are a few case reports on nail findings after coronavirus (COVID-19) infection. We aimed to document the nail findings of the COVID-19 survivors and shed light on the interesting luminescence seen under the Wood's light. METHODS: One hundred and seventy-four patients diagnosed with COVID-19 infection in the last 100 days were grouped in terms of the agents used in the treatment. Fifty-seven volunteers without a history of infection were included. RESULTS: Patients treated with favipiravir had a significantly higher positivity of luminescence (p: 0.0001). The most common nail findings in patients were splinter hemorrhage (13%), followed by leukonychia (12%) and longitudinal ridges (7.9%). DISCUSSION/CONCLUSIONS: The luminescence may be seen due to the accumulation of favipiravir or its excipients (titanium dioxide and yellow ferric oxide) on the nails. Wood's lamp examination of the plasma taken from a patient after favipiravir's first dose revealed the same luminescence as we saw on the nails. Accordingly, this accumulation may be seen in the vital organs. Although our knowledge about the virus increases day by day, the potentially hazardous effects of the virus and long-term complications of the treatment options are still being investigated.
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spelling pubmed-86782372021-12-17 Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination Yanatma, Irem Cenk, Hulya Skin Appendage Disord Clinical Investigations − Research Article INTRODUCTION: Various skin findings due to coronavirus have been identified. There are a few case reports on nail findings after coronavirus (COVID-19) infection. We aimed to document the nail findings of the COVID-19 survivors and shed light on the interesting luminescence seen under the Wood's light. METHODS: One hundred and seventy-four patients diagnosed with COVID-19 infection in the last 100 days were grouped in terms of the agents used in the treatment. Fifty-seven volunteers without a history of infection were included. RESULTS: Patients treated with favipiravir had a significantly higher positivity of luminescence (p: 0.0001). The most common nail findings in patients were splinter hemorrhage (13%), followed by leukonychia (12%) and longitudinal ridges (7.9%). DISCUSSION/CONCLUSIONS: The luminescence may be seen due to the accumulation of favipiravir or its excipients (titanium dioxide and yellow ferric oxide) on the nails. Wood's lamp examination of the plasma taken from a patient after favipiravir's first dose revealed the same luminescence as we saw on the nails. Accordingly, this accumulation may be seen in the vital organs. Although our knowledge about the virus increases day by day, the potentially hazardous effects of the virus and long-term complications of the treatment options are still being investigated. S. Karger AG 2022-03 2021-10-12 /pmc/articles/PMC8678237/ /pubmed/34934766 http://dx.doi.org/10.1159/000518983 Text en Copyright © 2021 by S. Karger AG, Basel
spellingShingle Clinical Investigations − Research Article
Yanatma, Irem
Cenk, Hulya
Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination
title Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination
title_full Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination
title_fullStr Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination
title_full_unstemmed Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination
title_short Evaluation of Nail Findings in Patients with COVID-19 History and Wood's Lamp Examination
title_sort evaluation of nail findings in patients with covid-19 history and wood's lamp examination
topic Clinical Investigations − Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678237/
https://www.ncbi.nlm.nih.gov/pubmed/34934766
http://dx.doi.org/10.1159/000518983
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