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Antibody Drug Conjugates in Glioblastoma – Is There a Future for Them?

Glioblastoma (GBM) is an aggressive and fatal malignancy that despite decades of trials has limited therapeutic options. Antibody drug conjugates (ADCs) are composed of a monoclonal antibody which specifically recognizes a cellular surface antigen linked to a cytotoxic payload. ADCs have demonstrate...

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Detalles Bibliográficos
Autores principales: Parakh, Sagun, Nicolazzo, Joseph, Scott, Andrew M, Gan, Hui Kong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678283/
https://www.ncbi.nlm.nih.gov/pubmed/34926242
http://dx.doi.org/10.3389/fonc.2021.718590

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