Allopregnanolone Improves Locomotor Activity and Arousal in the Aged CGG Knock-in Mouse Model of Fragile X-Associated Tremor/Ataxia Syndrome

Carriers of the fragile X premutation (PM) can develop a variety of early neurological symptoms, including depression, anxiety and cognitive impairment as well as being at risk for developing the late-onset fragile X-associated tremor/ataxia syndrome (FXTAS). The absence of effective treatments for...

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Detalles Bibliográficos
Autores principales: Schwartzer, Jared J., Garcia-Arocena, Dolores, Jamal, Amanda, Izadi, Ali, Willemsen, Rob, Berman, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678485/
https://www.ncbi.nlm.nih.gov/pubmed/34924931
http://dx.doi.org/10.3389/fnins.2021.752973

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