Cargando…
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect
Osteoarthritis (OA) is a common articular ailment presented with cartilage loss and destruction that is common observed in the elderly population. Physalin A (PA), a natural bioactive withanolide, exerts anti-inflammatory residences in more than a few diseases; however, little is known about its eff...
Autores principales: | Lu, Rui, Yu, Xiaojun, Liang, Shuang, Cheng, Peng, Wang, Zhenggang, He, Zhi-yi, Lv, Zheng-tao, Wan, Junlai, Mo, Haokun, Zhu, Wen-tao, Chen, An-min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678602/ https://www.ncbi.nlm.nih.gov/pubmed/34925020 http://dx.doi.org/10.3389/fphar.2021.761922 |
Ejemplares similares
-
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF-κB and MAPK signalling transduction through integrin αVβ3
por: Wan, Junlai, et al.
Publicado: (2023) -
Therapeutic Applications of Physalins: Powerful Natural Weapons
por: Meira, Cássio Santana, et al.
Publicado: (2022) -
Bromelain Extract Exerts Antiarthritic Effects via Chondroprotection and the Suppression of TNF-α–Induced NF-κB and MAPK Signaling
por: Pothacharoen, Peraphan, et al.
Publicado: (2021) -
Discovery of physalin biosynthesis and structure modification of physalins in Physalis alkekengi L. var. Franchetii
por: Qu, Liyuan, et al.
Publicado: (2022) -
Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway
por: Lv, Xin, et al.
Publicado: (2021)