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Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania
People with HIV (PWH) have a >2‐fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24‐h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case‐control study of ABPM in 137 PWH and HIV‐uninfected controls with...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678662/ https://www.ncbi.nlm.nih.gov/pubmed/34080288 http://dx.doi.org/10.1111/jch.14300 |
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author | Nolan, Cody Reis, Karl Fadhil, Salama Etyang, Anthony Ezeomah, Chiomah Kingery, Justin R. Desderius, Bernard Lee, Myung‐Hee Kapiga, Saidi Peck, Robert N. |
author_facet | Nolan, Cody Reis, Karl Fadhil, Salama Etyang, Anthony Ezeomah, Chiomah Kingery, Justin R. Desderius, Bernard Lee, Myung‐Hee Kapiga, Saidi Peck, Robert N. |
author_sort | Nolan, Cody |
collection | PubMed |
description | People with HIV (PWH) have a >2‐fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24‐h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case‐control study of ABPM in 137 PWH and HIV‐uninfected controls with normal and high clinic blood pressure (BP) in Tanzania. Nocturnal non‐dipping of heart rate (HR) was significantly more common among PWH than HIV‐uninfected controls (p = .01). Nocturnal non‐dipping of BP was significantly more common in PWH with normal clinic BP (p = .048). Clinical correlates of nocturnal non‐dipping were similar in PWH and HIV‐uninfected adults and included higher BMI, higher CD4(+) cell count, and high C‐reactive protein for HR and markers of renal disease for BP. In conclusion, nocturnal non‐dipping of both BP and HR was more common in PWH but further research is needed to determine causes and consequences of this difference. |
format | Online Article Text |
id | pubmed-8678662 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86786622021-12-23 Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania Nolan, Cody Reis, Karl Fadhil, Salama Etyang, Anthony Ezeomah, Chiomah Kingery, Justin R. Desderius, Bernard Lee, Myung‐Hee Kapiga, Saidi Peck, Robert N. J Clin Hypertens (Greenwich) Short Research Articles People with HIV (PWH) have a >2‐fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24‐h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case‐control study of ABPM in 137 PWH and HIV‐uninfected controls with normal and high clinic blood pressure (BP) in Tanzania. Nocturnal non‐dipping of heart rate (HR) was significantly more common among PWH than HIV‐uninfected controls (p = .01). Nocturnal non‐dipping of BP was significantly more common in PWH with normal clinic BP (p = .048). Clinical correlates of nocturnal non‐dipping were similar in PWH and HIV‐uninfected adults and included higher BMI, higher CD4(+) cell count, and high C‐reactive protein for HR and markers of renal disease for BP. In conclusion, nocturnal non‐dipping of both BP and HR was more common in PWH but further research is needed to determine causes and consequences of this difference. John Wiley and Sons Inc. 2021-06-02 /pmc/articles/PMC8678662/ /pubmed/34080288 http://dx.doi.org/10.1111/jch.14300 Text en © 2021 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Short Research Articles Nolan, Cody Reis, Karl Fadhil, Salama Etyang, Anthony Ezeomah, Chiomah Kingery, Justin R. Desderius, Bernard Lee, Myung‐Hee Kapiga, Saidi Peck, Robert N. Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
title | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
title_full | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
title_fullStr | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
title_full_unstemmed | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
title_short | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
title_sort | nocturnal dipping of heart rate and blood pressure in people with hiv in tanzania |
topic | Short Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678662/ https://www.ncbi.nlm.nih.gov/pubmed/34080288 http://dx.doi.org/10.1111/jch.14300 |
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