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Interaction of Cigarette Smoking and Polygenic Risk Score on Reduced Lung Function

IMPORTANCE: The risk of airflow limitation and chronic obstructive pulmonary disease (COPD) is influenced by combinations of cigarette smoking and genetic susceptibility, yet it remains unclear whether gene-by-smoking interactions are associated with quantitative measures of lung function. OBJECTIVE...

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Detalles Bibliográficos
Autores principales:	Kim, Woori, Moll, Matthew, Qiao, Dandi, Hobbs, Brian D., Shrine, Nick, Sakornsakolpat, Phuwanat, Tobin, Martin D., Dudbridge, Frank, Wain, Louise V., Ladd-Acosta, Christine, Chatterjee, Nilanjan, Silverman, Edwin K., Cho, Michael H., Beaty, Terri H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2021
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678715/ https://www.ncbi.nlm.nih.gov/pubmed/34913977 http://dx.doi.org/10.1001/jamanetworkopen.2021.39525

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