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Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence

Improved understanding of the current burden of hypertension, including awareness, treatment, and control, is needed to guide relevant preventative measures in Nigeria. A systematic search of studies on the epidemiology of hypertension in Nigeria, published on or after January 1990, was conducted. T...

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Autores principales: Adeloye, Davies, Owolabi, Eyitayo O., Ojji, Dike B., Auta, Asa, Dewan, Mary T., Olanrewaju, Timothy O., Ogah, Okechukwu S., Omoyele, Chiamaka, Ezeigwe, Nnenna, Mpazanje, Rex G., Gadanya, Muktar A., Agogo, Emmanuel, Alemu, Wondimagegnehu, Adebiyi, Akindele O., Harhay, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678849/
https://www.ncbi.nlm.nih.gov/pubmed/33600078
http://dx.doi.org/10.1111/jch.14220
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author Adeloye, Davies
Owolabi, Eyitayo O.
Ojji, Dike B.
Auta, Asa
Dewan, Mary T.
Olanrewaju, Timothy O.
Ogah, Okechukwu S.
Omoyele, Chiamaka
Ezeigwe, Nnenna
Mpazanje, Rex G.
Gadanya, Muktar A.
Agogo, Emmanuel
Alemu, Wondimagegnehu
Adebiyi, Akindele O.
Harhay, Michael O.
author_facet Adeloye, Davies
Owolabi, Eyitayo O.
Ojji, Dike B.
Auta, Asa
Dewan, Mary T.
Olanrewaju, Timothy O.
Ogah, Okechukwu S.
Omoyele, Chiamaka
Ezeigwe, Nnenna
Mpazanje, Rex G.
Gadanya, Muktar A.
Agogo, Emmanuel
Alemu, Wondimagegnehu
Adebiyi, Akindele O.
Harhay, Michael O.
author_sort Adeloye, Davies
collection PubMed
description Improved understanding of the current burden of hypertension, including awareness, treatment, and control, is needed to guide relevant preventative measures in Nigeria. A systematic search of studies on the epidemiology of hypertension in Nigeria, published on or after January 1990, was conducted. The authors employed random‐effects meta‐analysis on extracted crude hypertension prevalence, and awareness, treatment, and control rates. Using a meta‐regression model, overall hypertension cases in Nigeria in 1995 and 2020 were estimated. Fifty‐three studies (n = 78 949) met our selection criteria. Estimated crude prevalence of pre‐hypertension (120‐139/80‐89 mmHg) in Nigeria was 30.9% (95% confidence interval [CI]: 22.0%‐39.7%), and the crude prevalence of hypertension (≥140/90 mmHg) was 30.6% (95% CI: 27.3%‐34.0%). When adjusted for age, study period, and sample, absolute cases of hypertension increased by 540% among individuals aged ≥20 years from approximately 4.3 million individuals in 1995 (age‐adjusted prevalence 8.6%, 95% CI: 6.5‐10.7) to 27.5 million individuals with hypertension in 2020 (age‐adjusted prevalence 32.5%, 95% CI: 29.8‐35.3). The age‐adjusted prevalence was only significantly higher among men in 1995, with the gap between both sexes considerably narrowed in 2020. Only 29.0% of cases (95% CI: 19.7‐38.3) were aware of their hypertension, 12.0% (95% CI: 2.7‐21.2) were on treatment, and 2.8% (95% CI: 0.1‐5.7) had at‐goal blood pressure in 2020. Our study suggests that hypertension prevalence has substantially increased in Nigeria over the last two decades. Although more persons are aware of their hypertension status, clinical treatment and control rates, however, remain low. These estimates are relevant for clinical care, population, and policy response in Nigeria and across Africa.
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spelling pubmed-86788492021-12-23 Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence Adeloye, Davies Owolabi, Eyitayo O. Ojji, Dike B. Auta, Asa Dewan, Mary T. Olanrewaju, Timothy O. Ogah, Okechukwu S. Omoyele, Chiamaka Ezeigwe, Nnenna Mpazanje, Rex G. Gadanya, Muktar A. Agogo, Emmanuel Alemu, Wondimagegnehu Adebiyi, Akindele O. Harhay, Michael O. J Clin Hypertens (Greenwich) Epidemiology Improved understanding of the current burden of hypertension, including awareness, treatment, and control, is needed to guide relevant preventative measures in Nigeria. A systematic search of studies on the epidemiology of hypertension in Nigeria, published on or after January 1990, was conducted. The authors employed random‐effects meta‐analysis on extracted crude hypertension prevalence, and awareness, treatment, and control rates. Using a meta‐regression model, overall hypertension cases in Nigeria in 1995 and 2020 were estimated. Fifty‐three studies (n = 78 949) met our selection criteria. Estimated crude prevalence of pre‐hypertension (120‐139/80‐89 mmHg) in Nigeria was 30.9% (95% confidence interval [CI]: 22.0%‐39.7%), and the crude prevalence of hypertension (≥140/90 mmHg) was 30.6% (95% CI: 27.3%‐34.0%). When adjusted for age, study period, and sample, absolute cases of hypertension increased by 540% among individuals aged ≥20 years from approximately 4.3 million individuals in 1995 (age‐adjusted prevalence 8.6%, 95% CI: 6.5‐10.7) to 27.5 million individuals with hypertension in 2020 (age‐adjusted prevalence 32.5%, 95% CI: 29.8‐35.3). The age‐adjusted prevalence was only significantly higher among men in 1995, with the gap between both sexes considerably narrowed in 2020. Only 29.0% of cases (95% CI: 19.7‐38.3) were aware of their hypertension, 12.0% (95% CI: 2.7‐21.2) were on treatment, and 2.8% (95% CI: 0.1‐5.7) had at‐goal blood pressure in 2020. Our study suggests that hypertension prevalence has substantially increased in Nigeria over the last two decades. Although more persons are aware of their hypertension status, clinical treatment and control rates, however, remain low. These estimates are relevant for clinical care, population, and policy response in Nigeria and across Africa. John Wiley and Sons Inc. 2021-02-18 /pmc/articles/PMC8678849/ /pubmed/33600078 http://dx.doi.org/10.1111/jch.14220 Text en © 2021 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Epidemiology
Adeloye, Davies
Owolabi, Eyitayo O.
Ojji, Dike B.
Auta, Asa
Dewan, Mary T.
Olanrewaju, Timothy O.
Ogah, Okechukwu S.
Omoyele, Chiamaka
Ezeigwe, Nnenna
Mpazanje, Rex G.
Gadanya, Muktar A.
Agogo, Emmanuel
Alemu, Wondimagegnehu
Adebiyi, Akindele O.
Harhay, Michael O.
Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence
title Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence
title_full Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence
title_fullStr Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence
title_full_unstemmed Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence
title_short Prevalence, awareness, treatment, and control of hypertension in Nigeria in 1995 and 2020: A systematic analysis of current evidence
title_sort prevalence, awareness, treatment, and control of hypertension in nigeria in 1995 and 2020: a systematic analysis of current evidence
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678849/
https://www.ncbi.nlm.nih.gov/pubmed/33600078
http://dx.doi.org/10.1111/jch.14220
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