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Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results

BACKGROUND: Abdominal pain in chronic pancreatitis (CP) may require invasive interventions. Surgical procedures are rare, and little is known about the long-term results. AIM: To study the nationwide frequency of pancreatic surgery for CP in Finland, and postoperative symptoms and quality of life (Q...

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Autores principales: Parhiala, Mikael, Sand, Juhani, Laukkarinen, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678871/
https://www.ncbi.nlm.nih.gov/pubmed/35047603
http://dx.doi.org/10.12998/wjcc.v9.i35.10927
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author Parhiala, Mikael
Sand, Juhani
Laukkarinen, Johanna
author_facet Parhiala, Mikael
Sand, Juhani
Laukkarinen, Johanna
author_sort Parhiala, Mikael
collection PubMed
description BACKGROUND: Abdominal pain in chronic pancreatitis (CP) may require invasive interventions. Surgical procedures are rare, and little is known about the long-term results. AIM: To study the nationwide frequency of pancreatic surgery for CP in Finland, and postoperative symptoms and quality of life (QoL). METHODS: All patients in Finland with a diagnosis of CP who had undergone pancreatic surgery during 2000-2008 were selected from a national register. Only patients with CP as an indication for pancreatic surgery were included. Medical records were studied and questionnaires QLQ-C30, PAN26 and AUDIT, and symptom questionnaires were sent out. RESULTS: During the 9-year period, pancreatic surgery for CP was performed on 30 patients [77% men, median age 45 (21-62) years]. Eighty-three percent underwent endoscopic procedures before surgery. Surgery was performed a median 2 (0-10) years after the original CP diagnosis, and 17% developed postoperative complications. Primary pain relief after surgery was reported in 70% of cases. Need for strong pain medication was lower after surgery. Eight of 21 (38%) returned the questionnaires and 88% reported that surgery had reduced their pain and 63% were almost or entirely pain-free at a median 14 (10-18) years after surgery. QoL results did not differ from those in our control Finnish CP group. CONCLUSION: Surgery for CP is rare in Finland and most patients had prior endoscopic procedures. Patients who returned the questionnaires reported less pain and good QoL during the 14-year follow-up.
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spelling pubmed-86788712022-01-18 Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results Parhiala, Mikael Sand, Juhani Laukkarinen, Johanna World J Clin Cases Observational Study BACKGROUND: Abdominal pain in chronic pancreatitis (CP) may require invasive interventions. Surgical procedures are rare, and little is known about the long-term results. AIM: To study the nationwide frequency of pancreatic surgery for CP in Finland, and postoperative symptoms and quality of life (QoL). METHODS: All patients in Finland with a diagnosis of CP who had undergone pancreatic surgery during 2000-2008 were selected from a national register. Only patients with CP as an indication for pancreatic surgery were included. Medical records were studied and questionnaires QLQ-C30, PAN26 and AUDIT, and symptom questionnaires were sent out. RESULTS: During the 9-year period, pancreatic surgery for CP was performed on 30 patients [77% men, median age 45 (21-62) years]. Eighty-three percent underwent endoscopic procedures before surgery. Surgery was performed a median 2 (0-10) years after the original CP diagnosis, and 17% developed postoperative complications. Primary pain relief after surgery was reported in 70% of cases. Need for strong pain medication was lower after surgery. Eight of 21 (38%) returned the questionnaires and 88% reported that surgery had reduced their pain and 63% were almost or entirely pain-free at a median 14 (10-18) years after surgery. QoL results did not differ from those in our control Finnish CP group. CONCLUSION: Surgery for CP is rare in Finland and most patients had prior endoscopic procedures. Patients who returned the questionnaires reported less pain and good QoL during the 14-year follow-up. Baishideng Publishing Group Inc 2021-12-16 2021-12-16 /pmc/articles/PMC8678871/ /pubmed/35047603 http://dx.doi.org/10.12998/wjcc.v9.i35.10927 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Observational Study
Parhiala, Mikael
Sand, Juhani
Laukkarinen, Johanna
Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results
title Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results
title_full Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results
title_fullStr Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results
title_full_unstemmed Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results
title_short Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results
title_sort surgery for chronic pancreatitis in finland is rare but seems to produce good long-term results
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678871/
https://www.ncbi.nlm.nih.gov/pubmed/35047603
http://dx.doi.org/10.12998/wjcc.v9.i35.10927
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