Cargando…

Topical or oral antibiotics for children with acute otitis media presenting with ear discharge: study protocol of a randomised controlled non-inferiority trial

BACKGROUND: Around 15%–20% of children with acute otitis media present with ear discharge due to a spontaneous tear or perforation of the eardrum (AOMd). Current guidance recommends clinicians to consider oral antibiotics as first-line treatment in this condition. The opening in the eardrum however...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hullegie, Saskia, Venekamp, Roderick P, van Dongen, Thijs M A, Mulder, Sanne, van Schaik, Willem, de Wit, G Ardine, Hay, Alastair D, Little, Paul, Moore, Michael V, Sanders, Elisabeth A M, Bonten, Marc J M, Bogaert, Debby, Schilder, Anne GM, Damoiseaux, Roger A M J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	General practice / Family practice
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679066/ https://www.ncbi.nlm.nih.gov/pubmed/34916313 http://dx.doi.org/10.1136/bmjopen-2021-052128

Ejemplares similares

Effectiveness of analgesic ear drops as add-on treatment to oral analgesics in children with acute otitis media: study protocol of the OPTIMA pragmatic randomised controlled trial
por: de Sévaux, Joline L H, et al.
Publicado: (2023)

Prevalence and Antimicrobial Resistance of Bacteria in Children With Acute Otitis Media and Ear Discharge: A Systematic Review
por: Hullegie, Saskia, et al.
Publicado: (2021)

Identifying adults with acute rhinosinusitis in primary care that benefit most from antibiotics: protocol of an individual patient data meta-analysis using multivariable risk prediction modelling
por: Venekamp, Roderick P, et al.
Publicado: (2021)

Accuracy of signs, symptoms and blood tests for diagnosing acute bacterial rhinosinusitis and CT-confirmed acute rhinosinusitis in adults: protocol of an individual patient data meta-analysis
por: Venekamp, Roderick, et al.
Publicado: (2020)

Optimising telephone triage of patients calling for acute shortness of breath during out-of-hours primary care: protocol of a multiple methods study (Opticall)
por: Spek, Michelle, et al.
Publicado: (2022)

Optimising pain management in children with acute otitis media through a primary care-based multifaceted educational intervention: study protocol for a cluster randomised controlled trial
por: van Uum, Rick T., et al.
Publicado: (2018)

Cost of childhood acute otitis media in primary care in the Netherlands: economic analysis alongside a cluster randomised controlled trial
por: van Uum, Rick T., et al.
Publicado: (2021)

Prospective, observational study comparing automated and visual point-of-care urinalysis in general practice
por: van Delft, Sanne, et al.
Publicado: (2016)

Reducing unnecessary vitamin testing in general practice: barriers and facilitators according to general practitioners and patients
por: Hofstede, H., et al.
Publicado: (2019)

Pain management in acute otitis media: a qualitative study of parents’ views and expectations
por: van Uum, Rick T., et al.
Publicado: (2019)

Xylitol for the prevention of acute otitis media episodes in children aged 2–4 years: protocol for a pragmatic randomised controlled trial
por: Persaud, Nav, et al.
Publicado: (2018)

Recruitment challenges to the I CARE study: a randomised trial on general practitioner-led colon cancer survivorship care
por: Duineveld, Laura A M, et al.
Publicado: (2021)

Development and validation of a prediction rule for patients suspected of acute coronary syndrome in primary care: a cross-sectional study
por: Wouters, Loes T C M, et al.
Publicado: (2022)

Ruling out acute coronary syndrome in primary care with a clinical decision rule and a capillary, high-sensitive troponin I point of care test: study protocol of a diagnostic RCT in the Netherlands (POB HELP)
por: van den Bulk, Simone, et al.
Publicado: (2023)

A Systematic Review of Antibiotic Prescription for Acute Otitis Externa
por: Mughal, Zahir, et al.
Publicado: (2021)

Primary care-led survivorship care for patients with colon cancer and the use of eHealth: a qualitative study on perspectives of general practitioners
por: Duineveld, Laura A M, et al.
Publicado: (2016)

Relationship of Hearing Loss and Tympanic Membrane Perforation Characteristics in Chronic Suppurative Otitis Media Patients
por: Khurshid, Nawal, et al.
Publicado: (2022)

Pain management in acute otitis media: a qualitative study exploring GPs’ views and expectations parallel to a trial of an educational intervention
por: van Uum, Rick T, et al.
Publicado: (2018)

Qualitative interview study of parents’ perspectives, concerns and experiences of the management of lower respiratory tract infections in children in primary care
por: Halls, Amy, et al.
Publicado: (2017)

Mucosal Type of Chronic Suppurative Otitis Media and the Long-Term Impact on Hearing Loss
por: Rajput, Muhammad Salar-e-Azam, et al.
Publicado: (2020)

Chronic Suppurative Otitis Media: A Comprehensive Review of Epidemiology, Pathogenesis, Microbiology, and Complications
por: Khairkar, Mihika, et al.
Publicado: (2023)

Is the time of calling helpful for differentiating transient ischaemic attack and stroke from mimics in primary care out-of-hours services? A cross-sectional study
por: Erkelens, Daphne CA, et al.
Publicado: (2020)

A Strong Decline in the Incidence of Childhood Otitis Media During the COVID-19 Pandemic in the Netherlands
por: Hullegie, Saskia, et al.
Publicado: (2021)

Child and adolescent musculoskeletal pain (CAM-Pain) feasibility study: testing a method of identifying, recruiting and collecting data from children and adolescents who consult about a musculoskeletal condition in UK general practice
por: Michaleff, Zoe A, et al.
Publicado: (2018)

Impact of acute otitis media clinical practice guidelines on antibiotic and analgesic prescriptions: a systematic review
por: Deniz, Yelin, et al.
Publicado: (2018)

Improving pain management in childhood acute otitis media in general practice: a cluster randomised controlled trial of a GP-targeted educational intervention
por: van Uum, Rick T, et al.
Publicado: (2020)

Anticipated significant work limitation in primary care consulters with osteoarthritis: a prospective cohort study
por: Wilkie, Ross, et al.
Publicado: (2014)

Electronically delivered, multicomponent intervention to reduce unnecessary antibiotic prescribing for respiratory infections in primary care: a cluster randomised trial using electronic health records—REDUCE Trial study original protocol
por: Juszczyk, Dorota, et al.
Publicado: (2016)

Feasibility cluster randomised controlled trial of a within-consultation intervention to reduce antibiotic prescribing for children presenting to primary care with acute respiratory tract infection and cough
por: Blair, Peter S, et al.
Publicado: (2017)

Understanding the delayed prescribing of antibiotics for respiratory tract infection in primary care: a qualitative analysis
por: Ryves, R, et al.
Publicado: (2016)

Prediction of liver disease in patients whose liver function tests have been checked in primary care: model development and validation using population-based observational cohorts
por: McLernon, David J, et al.
Publicado: (2014)

Study protocol of the BLANKET trial: a cluster randomised controlled trial on the (cost-) effectiveness of a primary care intervention for fear of cancer recurrence in cancer survivors
por: Luigjes-Huizer, Yvonne L, et al.
Publicado: (2019)

Antibiotic-induced changes in the human gut microbiota for the most commonly prescribed antibiotics in primary care in the UK: a systematic review
por: Elvers, Karen T, et al.
Publicado: (2020)

Developing a clinical prediction rule for repeated consultations with functional somatic symptoms in primary care: a cohort study
por: Holtman, Gea A, et al.
Publicado: (2021)

Who are the patients being offered the faecal immunochemical test in routine English general practice, and for what symptoms? A prospective descriptive study
por: Calanzani, Natalia, et al.
Publicado: (2022)

Different potencies of topical corticosteroids for a better treatment strategy in children with atopic dermatitis (the Rotterdam Eczema study): protocol for an observational cohort study with an embedded randomised open-label controlled trial
por: van Halewijn, Karlijn F, et al.
Publicado: (2019)

Qualitative interview study of antibiotics and self-management strategies for respiratory infections in primary care
por: McDermott, Lisa, et al.
Publicado: (2017)

Lessons learnt from a cluster-randomised trial evaluating the effectiveness of Self-Management Support (SMS) delivered by practice nurses in routine diabetes care
por: van Dijk-de Vries, Anneke, et al.
Publicado: (2015)

Impact of digital interdisciplinary consultation on secondary care referrals by general practitioners: a protocol for a stepped-wedge cluster randomised controlled trial
por: Sanavro, Sanne, et al.
Publicado: (2022)

Invasive Pneumococcal Disease Secondary to Acute Otitis Media in a High-Risk Patient: A Case Report and Review of Recent Changes to Pneumococcal Immunization Guidelines
por: Gregory, Joshua, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pop9nlbbm976mk04flka9grfee