Cargando…

Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study

OBJECTIVES: To explore the prevalence and risk factors of metabolic-associated fatty liver disease (MAFLD) in Tianjin government employees of different genders. DESIGN: Cross-sectional study. SETTING: Health Management Center of Tianjin Union Medical Center. PARTICIPANTS: 16 924 government employees...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Ya-Ping, Zhang, Shi, Zhang, Minying, Wang, Yi, Wang, Wen-Hong, Li, Jing, Li, Chunjun, Lin, Jing-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679074/
https://www.ncbi.nlm.nih.gov/pubmed/34911725
http://dx.doi.org/10.1136/bmjopen-2021-056260
_version_ 1784616439412424704
author Huang, Ya-Ping
Zhang, Shi
Zhang, Minying
Wang, Yi
Wang, Wen-Hong
Li, Jing
Li, Chunjun
Lin, Jing-Na
author_facet Huang, Ya-Ping
Zhang, Shi
Zhang, Minying
Wang, Yi
Wang, Wen-Hong
Li, Jing
Li, Chunjun
Lin, Jing-Na
author_sort Huang, Ya-Ping
collection PubMed
description OBJECTIVES: To explore the prevalence and risk factors of metabolic-associated fatty liver disease (MAFLD) in Tianjin government employees of different genders. DESIGN: Cross-sectional study. SETTING: Health Management Center of Tianjin Union Medical Center. PARTICIPANTS: 16 924 government employees (59.6% male). MEASURES: Ultrasound liver examination was performed to determine whether there is fat accumulation in the organ. Participants’ weight and height were measured, and body mass index (BMI) was calculated. RESULTS: The overall prevalence of MAFLD in this population was 40.76%. The rates were significantly higher in men (49.42%) than in women (27.97%). The prevalence of MAFLD was highest in men aged 40–49 years (54.04%) and women aged 60–69 years (43.44%). In all BMI groups, the prevalence was higher in men than that in women. In both genders, higher BMI was associated with the risk of MAFLD, especially for BMI ≥31.9 kg/m(2). CONCLUSIONS: The prevalence of MAFLD in government employees in Tianjin was significantly higher than the average level in China. The prevalence varied by sex and age group, and those with high BMI were at the highest risk of developing MAFLD.
format Online
Article
Text
id pubmed-8679074
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-86790742022-01-04 Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study Huang, Ya-Ping Zhang, Shi Zhang, Minying Wang, Yi Wang, Wen-Hong Li, Jing Li, Chunjun Lin, Jing-Na BMJ Open Diabetes and Endocrinology OBJECTIVES: To explore the prevalence and risk factors of metabolic-associated fatty liver disease (MAFLD) in Tianjin government employees of different genders. DESIGN: Cross-sectional study. SETTING: Health Management Center of Tianjin Union Medical Center. PARTICIPANTS: 16 924 government employees (59.6% male). MEASURES: Ultrasound liver examination was performed to determine whether there is fat accumulation in the organ. Participants’ weight and height were measured, and body mass index (BMI) was calculated. RESULTS: The overall prevalence of MAFLD in this population was 40.76%. The rates were significantly higher in men (49.42%) than in women (27.97%). The prevalence of MAFLD was highest in men aged 40–49 years (54.04%) and women aged 60–69 years (43.44%). In all BMI groups, the prevalence was higher in men than that in women. In both genders, higher BMI was associated with the risk of MAFLD, especially for BMI ≥31.9 kg/m(2). CONCLUSIONS: The prevalence of MAFLD in government employees in Tianjin was significantly higher than the average level in China. The prevalence varied by sex and age group, and those with high BMI were at the highest risk of developing MAFLD. BMJ Publishing Group 2021-12-15 /pmc/articles/PMC8679074/ /pubmed/34911725 http://dx.doi.org/10.1136/bmjopen-2021-056260 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Diabetes and Endocrinology
Huang, Ya-Ping
Zhang, Shi
Zhang, Minying
Wang, Yi
Wang, Wen-Hong
Li, Jing
Li, Chunjun
Lin, Jing-Na
Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study
title Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study
title_full Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study
title_fullStr Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study
title_full_unstemmed Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study
title_short Gender-specific prevalence of metabolic-associated fatty liver disease among government employees in Tianjin, China: a cross-sectional study
title_sort gender-specific prevalence of metabolic-associated fatty liver disease among government employees in tianjin, china: a cross-sectional study
topic Diabetes and Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679074/
https://www.ncbi.nlm.nih.gov/pubmed/34911725
http://dx.doi.org/10.1136/bmjopen-2021-056260
work_keys_str_mv AT huangyaping genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy
AT zhangshi genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy
AT zhangminying genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy
AT wangyi genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy
AT wangwenhong genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy
AT lijing genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy
AT lichunjun genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy
AT linjingna genderspecificprevalenceofmetabolicassociatedfattyliverdiseaseamonggovernmentemployeesintianjinchinaacrosssectionalstudy