Sodium selenate as a disease-modifying treatment for progressive supranuclear palsy: protocol for a phase 2, randomised, double-blind, placebo-controlled trial

INTRODUCTION: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder for which there are currently no disease-modifying therapies. The neuropathology of PSP is associated with the accumulation of hyperphosphorylated tau in the brain. We have previously shown that protein phosphatase 2...

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Detalles Bibliográficos
Autores principales: Vivash, Lucy, Bertram, Kelly L, Malpas, Charles B, Marotta, Cassandra, Harding, Ian H, Kolbe, Scott, Fielding, Joanne, Clough, Meaghan, Lewis, Simon J G, Tisch, Stephen, Evans, Andrew H, O’Sullivan, John D, Kimber, Thomas, Darby, David, Churilov, Leonid, Law, Meng, Hovens, Christopher M, Velakoulis, Dennis, O’Brien, Terence J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679117/
https://www.ncbi.nlm.nih.gov/pubmed/34916328
http://dx.doi.org/10.1136/bmjopen-2021-055019

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