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Circulating mitochondrial DNA copy numbers represent a sensitive marker for diagnosis and monitoring of disease activity in systemic lupus erythematosus

OBJECTIVES: Cell-free DNA is involved in the pathogenesis of systemic lupus erythematosus (SLE) but the clinical value of cell-free DNA measurements in SLE is unknown. Our aim was therefore to examine the utility of mitochondrial (mt) DNA and nuclear (n) DNA quantification in SLE. METHODS: EDTA plas...

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Detalles Bibliográficos
Autores principales:	Giaglis, Stavros, Daoudlarian, Douglas, Voll, Reinhard E, Kyburz, Diego, Venhoff, Nils, Walker, Ulrich A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Lupus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679121/ https://www.ncbi.nlm.nih.gov/pubmed/34916301 http://dx.doi.org/10.1136/rmdopen-2021-002010

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