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A DNAmCULTURE Epigenetic Fingerprint Recapitulates Physiological Aging
Aging elicits dramatic changes to DNA methylation (DNAm), however the causes and consequences of such alterations to the epigenome remain unclear. The utility of biomarkers of aging based on DNAm patterns would be greatly enhanced if in vitro models existed that recapitulated physiological phenotype...
Autores principales: | Minteer, Christopher, Morselli, Marco, Meer, Margarita, Cao, Jian, Lang, Sabine, Pellegrini, Matteo, Yan, Qin, Levine, Morgan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679434/ http://dx.doi.org/10.1093/geroni/igab046.018 |
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