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A DNAmCULTURE Epigenetic Fingerprint Recapitulates Physiological Aging

Aging elicits dramatic changes to DNA methylation (DNAm), however the causes and consequences of such alterations to the epigenome remain unclear. The utility of biomarkers of aging based on DNAm patterns would be greatly enhanced if in vitro models existed that recapitulated physiological phenotype...

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Detalles Bibliográficos
Autores principales: Minteer, Christopher, Morselli, Marco, Meer, Margarita, Cao, Jian, Lang, Sabine, Pellegrini, Matteo, Yan, Qin, Levine, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679434/
http://dx.doi.org/10.1093/geroni/igab046.018

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