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Acute exposure to extracellular BTP2 does not inhibit Ca(2+) release during EC coupling in intact skeletal muscle fibers

The inhibitor of store-operated Ca(2+) entry (SOCE) BTP2 was reported to inhibit ryanodine receptor Ca(2+) leak and electrically evoked Ca(2+) release from the sarcoplasmic reticulum when introduced into mechanically skinned muscle fibers. However, it is unclear how effects of intracellular applicat...

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Detalles Bibliográficos
Autores principales: Wei-LaPierre, Lan, Groom, Linda, Dirksen, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679509/
https://www.ncbi.nlm.nih.gov/pubmed/34910094
http://dx.doi.org/10.1085/jgp.202112976