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Human NLRP1: From the shadows to center stage

In response to infection or cell damage, inflammasomes form intracellular multimeric protein complexes that play an essential role in host defense. Activation results in the maturation and subsequent secretion of pro-inflammatory cytokines of the IL-1 family and a specific cell death coined pyroptos...

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Detalles Bibliográficos
Autores principales: Bauernfried, Stefan, Hornung, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679799/
https://www.ncbi.nlm.nih.gov/pubmed/34910085
http://dx.doi.org/10.1084/jem.20211405