Arginase II Promotes Intervertebral Disc Degeneration Through Exacerbating Senescence and Apoptosis Caused by Oxidative Stress and Inflammation via the NF-κB Pathway

Intervertebral disc degeneration (IDD) has been generally accepted as the major cause of low back pain (LBP), which imposes massive clinical and socioeconomic burdens. Previous studies have demonstrated that oxidative stress and inflammation-induced senescence and apoptosis of nucleus pulposus cells...

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Detalles Bibliográficos
Autores principales: Li, Fudong, Sun, Xiaofei, Zheng, Bing, Sun, Kaiqiang, Zhu, Jian, Ji, Chenglong, Lin, Feng, Huan, Le, Luo, Xi, Yan, Chen, Xu, Jiashun, Hong, Yun, Wang, Yuan, Xu, Ximing, Sun, Jingchuan, Song, Zheming, Kong, Fanqi, Shi, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679914/
https://www.ncbi.nlm.nih.gov/pubmed/34926442
http://dx.doi.org/10.3389/fcell.2021.737809

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