Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures

While understanding molecular heterogeneity across patients underpins precision oncology, there is increasing appreciation for taking intra-tumor heterogeneity into account. Based on large-scale analysis of cancer omics datasets, we highlight the importance of intra-tumor transcriptomic heterogeneit...

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Detalles Bibliográficos
Autores principales: Suphavilai, Chayaporn, Chia, Shumei, Sharma, Ankur, Tu, Lorna, Da Silva, Rafael Peres, Mongia, Aanchal, DasGupta, Ramanuj, Nagarajan, Niranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680165/
https://www.ncbi.nlm.nih.gov/pubmed/34915921
http://dx.doi.org/10.1186/s13073-021-01000-y

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