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The Frailty Syndrome: An Emergent Property of Parallel Dysregulation in Multiple Physiological Systems?

Despite its widespread presence in older adults, frailty etiology is still unclear, being associated with dysregulation in diverse physiological systems. Here, we show evidence that frailty emerges from broad loss of homeostasis integrated through complex systems dynamics. Using the NuAge and WHAS c...

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Detalles Bibliográficos
Autores principales: Cohen, Alan, Ghachem, Ahmed, Fried, Linda, Legault, Véronique, Bandeen-Roche, Karen, Presse, Nancy, Gaudreau, Pierrette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680250/
http://dx.doi.org/10.1093/geroni/igab046.1482