Cargando…
The Frailty Syndrome: An Emergent Property of Parallel Dysregulation in Multiple Physiological Systems?
Despite its widespread presence in older adults, frailty etiology is still unclear, being associated with dysregulation in diverse physiological systems. Here, we show evidence that frailty emerges from broad loss of homeostasis integrated through complex systems dynamics. Using the NuAge and WHAS c...
Autores principales: | Cohen, Alan, Ghachem, Ahmed, Fried, Linda, Legault, Véronique, Bandeen-Roche, Karen, Presse, Nancy, Gaudreau, Pierrette |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680250/ http://dx.doi.org/10.1093/geroni/igab046.1482 |
Ejemplares similares
-
Comparison of Different Approaches to Operationalize Fried’s Phenotypic Frailty in the NuAge Cohort
por: Turcot, Valerie, et al.
Publicado: (2021) -
Nutrient Intake Patterns Predict Homeostatic Dysregulation in an Older Quebec Population
por: Cohen, Alan, et al.
Publicado: (2020) -
Homeostatic dysregulation proceeds in parallel in multiple physiological systems
por: Li, Qing, et al.
Publicado: (2015) -
Understanding and Measuring Frailty: Insights From the Canadian NuAge and CLSA Cohorts
por: Gaudreau, Pierrette, et al.
Publicado: (2021) -
Multidimensional associations between nutrient intake and healthy ageing in humans
por: Senior, Alistair M., et al.
Publicado: (2022)