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NLRP1 inflammasome involves in learning and memory impairments and neuronal damages during aging process in mice
BACKGROUND: Brain aging is an important risk factor in many human diseases, such as Alzheimer’s disease (AD). The production of excess reactive oxygen species (ROS) mediated by nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) and the maturation of inflammatory cytokines caused by activat...
Autores principales: | Sun, Dan, Gao, Guofang, Zhong, Bihua, Zhang, Han, Ding, Shixin, Sun, Zhenghao, Zhang, Yaodong, Li, Weizu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680336/ https://www.ncbi.nlm.nih.gov/pubmed/34920732 http://dx.doi.org/10.1186/s12993-021-00185-x |
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