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Using Drosophila to Identify Naturally-Occurring Modifiers of Alzheimer's Disease

Despite significant progress in identifying risk factors for late-onset Alzheimer’s Disease (LOAD), much of the variance in disease pathogenesis remains unexplained, likely due to the contribution of many genes of small effect size. Model organisms such as Drosophila Melanogaster exhibit conservatio...

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Detalles Bibliográficos
Autores principales: Wang, Adrienne, Yang, Ming, Fitzgerald-Cook, Cecilia, Harrison, Ben, Green, Akimi, Hartman, Kensington, Zinkgraf, Matthew, Promislow, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680661/
http://dx.doi.org/10.1093/geroni/igab046.2425