Intratumor heterogeneity and clonal evolution revealed in castration-resistant prostate cancer by longitudinal genomic analysis

Intratumor heterogeneity is a key driver for local relapse and treatment failure. Thus, using multifocal prostate cancer as a model to investigate tumor inter-clonal relationships and tumor evolution could aid in our understanding of drug resistance. Previous studies discovered genomic alterations b...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhui, Wang, Tao, Wang, Yan, Zhu, Feng, Shi, Haoqing, Zhang, Jili, Wang, Ziwei, Qu, Min, Zhang, Huaru, Wang, Tianyi, Qian, Yuping, Yang, Jinjian, Gao, Xu, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681025/
https://www.ncbi.nlm.nih.gov/pubmed/34902740
http://dx.doi.org/10.1016/j.tranon.2021.101311

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