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Apolipoprotein E impairs aged bone fracture healing

Bone fracture healing and osteoblast differentiation are impaired with advanced age. Using a combination of parabiosis and proteomic models, we identified apolipoprotein E (ApoE) to be an aging factor in bone regeneration. Circulating levels of ApoE increased with age in patients and in mice. ApoE i...

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Detalles Bibliográficos
Autores principales:	Balu, Abhinav, Huang, Rong, Molitoris, Kristin, Baht, Gurpreet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681331/ http://dx.doi.org/10.1093/geroni/igab046.2499

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