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Hematopoietic mosaic chromosomal alterations in the New England Centenarian Study.

Mosaic chromosomal alterations (mCAs) are structural alterations that include deletions, duplications, or copy-neutral loss of heterozygosity. mCAs are reported to be associated with survival, age, cancer, and cardiovascular disease. Previous studies of mCAs in large population-based cohorts (UK Bio...

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Detalles Bibliográficos
Autores principales: Leshchyk, Anastasia, Genovese, Giulio, Monti, Stefano, Perls, Thomas, Sebastiani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681568/
http://dx.doi.org/10.1093/geroni/igab046.2544