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Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults

Depression in older adults is associated with loss of functioning and increased mortality. While many factors contribute to depression among this population, activities of daily living (ADL) limitations and cognitive impairment have been identified as key risk factors. However, no study, to our know...

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Autores principales: Scher, Clara, Amano, Takashi, Nepomnyaschy, Lenna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681844/
http://dx.doi.org/10.1093/geroni/igab046.3106
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author Scher, Clara
Amano, Takashi
Nepomnyaschy, Lenna
author_facet Scher, Clara
Amano, Takashi
Nepomnyaschy, Lenna
author_sort Scher, Clara
collection PubMed
description Depression in older adults is associated with loss of functioning and increased mortality. While many factors contribute to depression among this population, activities of daily living (ADL) limitations and cognitive impairment have been identified as key risk factors. However, no study, to our knowledge, has examined the extent to which physical and cognitive limitations independently and jointly contribute to the risk of depression. The current study describes the prevalence and compares the independent and joint associations of these limitations with depression in a nationally representative sample of adults aged 51 and older in the US. Analyses are based on a sample of 17,044 repeated observations on 6,636 unique primary respondents from three waves of pooled data from the Health and Retirement Study. We estimate linear and logistic multivariate regression models investigating the association between ADL limitations (any limitation on Katz ADL scale), cognitive impairment (<12 on the TICS-27 scale), and depressive symptoms (8-item CES-D), controlling for a standard set of socioeconomic and health factors. First, we find that 66% of respondents report no limitations, 16% report only cognitive impairment, 11% report only ADL limitations, and 7% report both types of limitations. Multivariate analyses suggest that ADL limitations have a much stronger association with depression compared to cognitive impairment, and this association is robust across alternative specifications. In next steps, we will take advantage of the longitudinal nature of these data to estimate changes in these characteristics over time and within individuals and explore heterogeneity in associations across relevant groups.
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spelling pubmed-86818442021-12-20 Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults Scher, Clara Amano, Takashi Nepomnyaschy, Lenna Innov Aging Abstracts Depression in older adults is associated with loss of functioning and increased mortality. While many factors contribute to depression among this population, activities of daily living (ADL) limitations and cognitive impairment have been identified as key risk factors. However, no study, to our knowledge, has examined the extent to which physical and cognitive limitations independently and jointly contribute to the risk of depression. The current study describes the prevalence and compares the independent and joint associations of these limitations with depression in a nationally representative sample of adults aged 51 and older in the US. Analyses are based on a sample of 17,044 repeated observations on 6,636 unique primary respondents from three waves of pooled data from the Health and Retirement Study. We estimate linear and logistic multivariate regression models investigating the association between ADL limitations (any limitation on Katz ADL scale), cognitive impairment (<12 on the TICS-27 scale), and depressive symptoms (8-item CES-D), controlling for a standard set of socioeconomic and health factors. First, we find that 66% of respondents report no limitations, 16% report only cognitive impairment, 11% report only ADL limitations, and 7% report both types of limitations. Multivariate analyses suggest that ADL limitations have a much stronger association with depression compared to cognitive impairment, and this association is robust across alternative specifications. In next steps, we will take advantage of the longitudinal nature of these data to estimate changes in these characteristics over time and within individuals and explore heterogeneity in associations across relevant groups. Oxford University Press 2021-12-17 /pmc/articles/PMC8681844/ http://dx.doi.org/10.1093/geroni/igab046.3106 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Scher, Clara
Amano, Takashi
Nepomnyaschy, Lenna
Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults
title Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults
title_full Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults
title_fullStr Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults
title_full_unstemmed Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults
title_short Comparing Cognitive and Physical Limitations as Predictors of Depression Among Older Adults
title_sort comparing cognitive and physical limitations as predictors of depression among older adults
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681844/
http://dx.doi.org/10.1093/geroni/igab046.3106
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