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Proteasome- and Calpain-Mediated Proteolysis, but Not Autophagy, Is Required for Leucine-Induced Protein Synthesis in C2C12 Myotubes
Muscle protein synthesis and proteolysis are tightly coupled processes. Given that muscle growth is promoted by increases in net protein balance, it stands to reason that bolstering protein synthesis through amino acids while reducing or inhibiting proteolysis could be a synergistic strategy in enha...
Autores principales: | Osburn, Shelby C., Vann, Christopher G., Church, David D., Ferrando, Arny A., Roberts, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681867/ https://www.ncbi.nlm.nih.gov/pubmed/34927140 http://dx.doi.org/10.3390/physiologia1010005 |
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