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Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry
BACKGROUND: Time spent sedentary increases with age and has several negative health consequences. We sought to examine associations between daily sedentary and active bout frequency with all-cause mortality. METHODS: Data are from 2,918 men in the Osteoporotic Fractures in Men (MrOS) study (mean age...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681899/ http://dx.doi.org/10.1093/geroni/igab046.3467 |
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author | Roe, Lauren S Harrison, Stephanie Cawthon, Peggy Moored, Kyle Ensrud, Kristine Stone, Katie Gabriel, Kelley Pettee Cauley, Jane |
author_facet | Roe, Lauren S Harrison, Stephanie Cawthon, Peggy Moored, Kyle Ensrud, Kristine Stone, Katie Gabriel, Kelley Pettee Cauley, Jane |
author_sort | Roe, Lauren S |
collection | PubMed |
description | BACKGROUND: Time spent sedentary increases with age and has several negative health consequences. We sought to examine associations between daily sedentary and active bout frequency with all-cause mortality. METHODS: Data are from 2,918 men in the Osteoporotic Fractures in Men (MrOS) study (mean age at Visit 3±SD: 79.0±5.1 years) with valid activity monitor data (5.1±0.3 days worn>90%) at Year 7 visit (Visit 3, 2007-2009). Sedentary and active bout frequencies are defined as the daily transition frequency from a sedentary bout lasting 5+ minutes to activity of any intensity, and the transition frequency from an active bout lasting 5+ minutes to sedentary. Deaths were centrally adjudicated using death certificates. Cox proportional hazard models were used to examine associations between quartiles of sedentary (Q1 referent, <13.6 bouts/day) or active (Q1 referent, <5 bouts/day) bout frequency and mortality. Models were repeated, stratifying by median daily total time spent sedentary and active. RESULTS: After 9.4±3.7 years of follow-up, 1,487 (51.0%) men died. Men averaged 16.9±5.1 and 8.2±4.2 sedentary and active bouts/day, respectively. After full covariate adjustment, each quartile reflecting a higher sedentary (Q4 vs Q1 HR: 0.68, 95%CI: 0.58-0.81, p-trend<0.001) and active bout (Q4 vs Q1 HR: 0.57, 95%CI: 0.48-0.68, p-trend<0.001) frequency was associated with lower mortality risk. There was no evidence that effects differed by total sedentary time (p-interaction for sedentary bout frequency and total sedentary time>0.05). CONCLUSIONS: More frequent, prolonged sedentary and active bouts are associated with a lower mortality risk in older men and is not moderated by total sedentary time. |
format | Online Article Text |
id | pubmed-8681899 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-86818992021-12-20 Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry Roe, Lauren S Harrison, Stephanie Cawthon, Peggy Moored, Kyle Ensrud, Kristine Stone, Katie Gabriel, Kelley Pettee Cauley, Jane Innov Aging Abstracts BACKGROUND: Time spent sedentary increases with age and has several negative health consequences. We sought to examine associations between daily sedentary and active bout frequency with all-cause mortality. METHODS: Data are from 2,918 men in the Osteoporotic Fractures in Men (MrOS) study (mean age at Visit 3±SD: 79.0±5.1 years) with valid activity monitor data (5.1±0.3 days worn>90%) at Year 7 visit (Visit 3, 2007-2009). Sedentary and active bout frequencies are defined as the daily transition frequency from a sedentary bout lasting 5+ minutes to activity of any intensity, and the transition frequency from an active bout lasting 5+ minutes to sedentary. Deaths were centrally adjudicated using death certificates. Cox proportional hazard models were used to examine associations between quartiles of sedentary (Q1 referent, <13.6 bouts/day) or active (Q1 referent, <5 bouts/day) bout frequency and mortality. Models were repeated, stratifying by median daily total time spent sedentary and active. RESULTS: After 9.4±3.7 years of follow-up, 1,487 (51.0%) men died. Men averaged 16.9±5.1 and 8.2±4.2 sedentary and active bouts/day, respectively. After full covariate adjustment, each quartile reflecting a higher sedentary (Q4 vs Q1 HR: 0.68, 95%CI: 0.58-0.81, p-trend<0.001) and active bout (Q4 vs Q1 HR: 0.57, 95%CI: 0.48-0.68, p-trend<0.001) frequency was associated with lower mortality risk. There was no evidence that effects differed by total sedentary time (p-interaction for sedentary bout frequency and total sedentary time>0.05). CONCLUSIONS: More frequent, prolonged sedentary and active bouts are associated with a lower mortality risk in older men and is not moderated by total sedentary time. Oxford University Press 2021-12-17 /pmc/articles/PMC8681899/ http://dx.doi.org/10.1093/geroni/igab046.3467 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstracts Roe, Lauren S Harrison, Stephanie Cawthon, Peggy Moored, Kyle Ensrud, Kristine Stone, Katie Gabriel, Kelley Pettee Cauley, Jane Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry |
title | Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry |
title_full | Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry |
title_fullStr | Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry |
title_full_unstemmed | Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry |
title_short | Association of Sedentary and Active Bout Frequency With Mortality in Older Men Using Accelerometry |
title_sort | association of sedentary and active bout frequency with mortality in older men using accelerometry |
topic | Abstracts |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681899/ http://dx.doi.org/10.1093/geroni/igab046.3467 |
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