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Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease.

Acculturative processes via persistent exposure to a set of cultural practices and behaviors can influence cognitive functioning (Park & Huang, 2010). The impact of acculturation on populations at risk for Alzheimer’s disease (AD), however, remains understudied. Persons with or at-risk for early...

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Autores principales: Tureson, Kayla, Beam, Christopher, Ringman, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681984/
http://dx.doi.org/10.1093/geroni/igab046.3659
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author Tureson, Kayla
Beam, Christopher
Ringman, John
author_facet Tureson, Kayla
Beam, Christopher
Ringman, John
author_sort Tureson, Kayla
collection PubMed
description Acculturative processes via persistent exposure to a set of cultural practices and behaviors can influence cognitive functioning (Park & Huang, 2010). The impact of acculturation on populations at risk for Alzheimer’s disease (AD), however, remains understudied. Persons with or at-risk for early-onset autosomal dominant AD (ADAD) offer a known AD pathogenesis and the opportunity to study whether acculturation moderates their cognitive performance. The present study used a latent variable model to test whether effects of latent cognitive ability on observable cognitive performance depend on acculturation. Participants included 119 adults with or at-risk for ADAD, the majority of whom were of Mexican origin with various levels of U.S. acculturation. Participants completed the Cognitive Abilities Screening Instrument (CASI) and the Acculturation Rating Scale for Mexican Americans-II (ARSMA-II). Confirmatory factor analysis was used to estimate a latent general cognitive ability factor from nine domains (e.g., attention, abstraction and judgment). The ARSMA-II was used to test whether factor loadings depended on level of acculturation, covarying for mutation status. Results revealed ARSMA-II scores nearly significantly moderated the effects of general cognitive ability on abstraction and judgment (λ = 0.20, SE = 0.11, p = .070). Individual differences in general cognitive ability at lower levels of acculturation likely predict lower abstraction and judgment performance. Cognitive assessments may not equally represent true cognitive ability in Mexican-Americans. Although the CASI was developed as a cross-cultural measure of cognitive functioning, caution should be exercised in inferring true cognitive functioning in Mexican-Americans who may not be acculturated to the U.S.
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spelling pubmed-86819842021-12-20 Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease. Tureson, Kayla Beam, Christopher Ringman, John Innov Aging Abstracts Acculturative processes via persistent exposure to a set of cultural practices and behaviors can influence cognitive functioning (Park & Huang, 2010). The impact of acculturation on populations at risk for Alzheimer’s disease (AD), however, remains understudied. Persons with or at-risk for early-onset autosomal dominant AD (ADAD) offer a known AD pathogenesis and the opportunity to study whether acculturation moderates their cognitive performance. The present study used a latent variable model to test whether effects of latent cognitive ability on observable cognitive performance depend on acculturation. Participants included 119 adults with or at-risk for ADAD, the majority of whom were of Mexican origin with various levels of U.S. acculturation. Participants completed the Cognitive Abilities Screening Instrument (CASI) and the Acculturation Rating Scale for Mexican Americans-II (ARSMA-II). Confirmatory factor analysis was used to estimate a latent general cognitive ability factor from nine domains (e.g., attention, abstraction and judgment). The ARSMA-II was used to test whether factor loadings depended on level of acculturation, covarying for mutation status. Results revealed ARSMA-II scores nearly significantly moderated the effects of general cognitive ability on abstraction and judgment (λ = 0.20, SE = 0.11, p = .070). Individual differences in general cognitive ability at lower levels of acculturation likely predict lower abstraction and judgment performance. Cognitive assessments may not equally represent true cognitive ability in Mexican-Americans. Although the CASI was developed as a cross-cultural measure of cognitive functioning, caution should be exercised in inferring true cognitive functioning in Mexican-Americans who may not be acculturated to the U.S. Oxford University Press 2021-12-17 /pmc/articles/PMC8681984/ http://dx.doi.org/10.1093/geroni/igab046.3659 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Tureson, Kayla
Beam, Christopher
Ringman, John
Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease.
title Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease.
title_full Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease.
title_fullStr Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease.
title_full_unstemmed Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease.
title_short Acculturation moderates cognitive performance in adults at risk of autosomal dominant Alzheimer's Disease.
title_sort acculturation moderates cognitive performance in adults at risk of autosomal dominant alzheimer's disease.
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681984/
http://dx.doi.org/10.1093/geroni/igab046.3659
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