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Protection against APOE4-associated aging phenotypes with a longevity-promoting intervention

Two of the primary risk factors for late onset Alzheimer’s Disease (AD) are aging and APOE genotype. While the causal relationship between aging and AD is not well defined, there are strong leads from shared phenotypes such as decreased metabolic function and increased inflammation. APOE genotype ma...

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Detalles Bibliográficos
Autores principales: McGill, Cassandra, Christensen, Amy, Qian, Wenjie, Finch, Caleb, Benayoun, Berenice, Pike, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682321/
http://dx.doi.org/10.1093/geroni/igab046.3427