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Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites
Latinos face a growing burden of Alzheimer’s Disease and related dementia (ADRD). Although education has been established as a strong predictor of ADRD, evidence to date is primarily for non-Latino cohorts. Few studies have assessed the relationship between intergenerational education and one’s cogn...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682417/ http://dx.doi.org/10.1093/geroni/igab046.3308 |
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author | Meza, Erika Chen, Yea-Hung Allen, Isabel Gonzalez, Hector Glymour, M Maria Torres, Jacqueline |
author_facet | Meza, Erika Chen, Yea-Hung Allen, Isabel Gonzalez, Hector Glymour, M Maria Torres, Jacqueline |
author_sort | Meza, Erika |
collection | PubMed |
description | Latinos face a growing burden of Alzheimer’s Disease and related dementia (ADRD). Although education has been established as a strong predictor of ADRD, evidence to date is primarily for non-Latino cohorts. Few studies have assessed the relationship between intergenerational education and one’s cognitive decline. Using the US Health and Retirement Study (N=20,860) we evaluated the joint effect of parental and own educational attainment on immediate and delayed verbal memory scores (range 0-10) from 1998 to 2016. The exposure was a 4-category variable based on parents’ (highest of mother’s or father’s) and participant’s own high school attainment: first-generation (parents’ education <12; own ≥12); multi-generation (both ≥12: REF); neither graduated high school (both <12) and parent(s) graduated high school but not respondent (parents ≥12; own <12). Linear mixed effects models with subject-specific random intercepts and random slopes were stratified by race/ethnicity and tested for a 3-way interaction term (exposure x Latino x time). Models controlled for age, sex, place of birth and retest effects. Baseline verbal memory scores did not differ for first-generation compared to multi-generation high school graduates. Verbal memory decline was faster for first- compared to multi-generation high school graduates among non-Hispanic whites (e.g., β=-0.04; 95% CI: -0.05, -0.03, delayed verbal recall); among Latinos, first and multi-generation high school graduates had similar rates of decline (e.g. β=0.00; 95% CI: -0.03, 0.04, delayed verbal recall; p<0.001 for three-way interaction). Our findings suggest social and economic policies that facilitate educational achievement, particularly for important population subgroups, may reduce ADRD risk. |
format | Online Article Text |
id | pubmed-8682417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-86824172021-12-20 Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites Meza, Erika Chen, Yea-Hung Allen, Isabel Gonzalez, Hector Glymour, M Maria Torres, Jacqueline Innov Aging Abstracts Latinos face a growing burden of Alzheimer’s Disease and related dementia (ADRD). Although education has been established as a strong predictor of ADRD, evidence to date is primarily for non-Latino cohorts. Few studies have assessed the relationship between intergenerational education and one’s cognitive decline. Using the US Health and Retirement Study (N=20,860) we evaluated the joint effect of parental and own educational attainment on immediate and delayed verbal memory scores (range 0-10) from 1998 to 2016. The exposure was a 4-category variable based on parents’ (highest of mother’s or father’s) and participant’s own high school attainment: first-generation (parents’ education <12; own ≥12); multi-generation (both ≥12: REF); neither graduated high school (both <12) and parent(s) graduated high school but not respondent (parents ≥12; own <12). Linear mixed effects models with subject-specific random intercepts and random slopes were stratified by race/ethnicity and tested for a 3-way interaction term (exposure x Latino x time). Models controlled for age, sex, place of birth and retest effects. Baseline verbal memory scores did not differ for first-generation compared to multi-generation high school graduates. Verbal memory decline was faster for first- compared to multi-generation high school graduates among non-Hispanic whites (e.g., β=-0.04; 95% CI: -0.05, -0.03, delayed verbal recall); among Latinos, first and multi-generation high school graduates had similar rates of decline (e.g. β=0.00; 95% CI: -0.03, 0.04, delayed verbal recall; p<0.001 for three-way interaction). Our findings suggest social and economic policies that facilitate educational achievement, particularly for important population subgroups, may reduce ADRD risk. Oxford University Press 2021-12-17 /pmc/articles/PMC8682417/ http://dx.doi.org/10.1093/geroni/igab046.3308 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstracts Meza, Erika Chen, Yea-Hung Allen, Isabel Gonzalez, Hector Glymour, M Maria Torres, Jacqueline Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites |
title | Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites |
title_full | Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites |
title_fullStr | Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites |
title_full_unstemmed | Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites |
title_short | Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites |
title_sort | intergenerational education and late-life cognitive decline among latinos and non-hispanic whites |
topic | Abstracts |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682417/ http://dx.doi.org/10.1093/geroni/igab046.3308 |
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