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Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites

Latinos face a growing burden of Alzheimer’s Disease and related dementia (ADRD). Although education has been established as a strong predictor of ADRD, evidence to date is primarily for non-Latino cohorts. Few studies have assessed the relationship between intergenerational education and one’s cogn...

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Autores principales: Meza, Erika, Chen, Yea-Hung, Allen, Isabel, Gonzalez, Hector, Glymour, M Maria, Torres, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682417/
http://dx.doi.org/10.1093/geroni/igab046.3308
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author Meza, Erika
Chen, Yea-Hung
Allen, Isabel
Gonzalez, Hector
Glymour, M Maria
Torres, Jacqueline
author_facet Meza, Erika
Chen, Yea-Hung
Allen, Isabel
Gonzalez, Hector
Glymour, M Maria
Torres, Jacqueline
author_sort Meza, Erika
collection PubMed
description Latinos face a growing burden of Alzheimer’s Disease and related dementia (ADRD). Although education has been established as a strong predictor of ADRD, evidence to date is primarily for non-Latino cohorts. Few studies have assessed the relationship between intergenerational education and one’s cognitive decline. Using the US Health and Retirement Study (N=20,860) we evaluated the joint effect of parental and own educational attainment on immediate and delayed verbal memory scores (range 0-10) from 1998 to 2016. The exposure was a 4-category variable based on parents’ (highest of mother’s or father’s) and participant’s own high school attainment: first-generation (parents’ education <12; own ≥12); multi-generation (both ≥12: REF); neither graduated high school (both <12) and parent(s) graduated high school but not respondent (parents ≥12; own <12). Linear mixed effects models with subject-specific random intercepts and random slopes were stratified by race/ethnicity and tested for a 3-way interaction term (exposure x Latino x time). Models controlled for age, sex, place of birth and retest effects. Baseline verbal memory scores did not differ for first-generation compared to multi-generation high school graduates. Verbal memory decline was faster for first- compared to multi-generation high school graduates among non-Hispanic whites (e.g., β=-0.04; 95% CI: -0.05, -0.03, delayed verbal recall); among Latinos, first and multi-generation high school graduates had similar rates of decline (e.g. β=0.00; 95% CI: -0.03, 0.04, delayed verbal recall; p<0.001 for three-way interaction). Our findings suggest social and economic policies that facilitate educational achievement, particularly for important population subgroups, may reduce ADRD risk.
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spelling pubmed-86824172021-12-20 Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites Meza, Erika Chen, Yea-Hung Allen, Isabel Gonzalez, Hector Glymour, M Maria Torres, Jacqueline Innov Aging Abstracts Latinos face a growing burden of Alzheimer’s Disease and related dementia (ADRD). Although education has been established as a strong predictor of ADRD, evidence to date is primarily for non-Latino cohorts. Few studies have assessed the relationship between intergenerational education and one’s cognitive decline. Using the US Health and Retirement Study (N=20,860) we evaluated the joint effect of parental and own educational attainment on immediate and delayed verbal memory scores (range 0-10) from 1998 to 2016. The exposure was a 4-category variable based on parents’ (highest of mother’s or father’s) and participant’s own high school attainment: first-generation (parents’ education <12; own ≥12); multi-generation (both ≥12: REF); neither graduated high school (both <12) and parent(s) graduated high school but not respondent (parents ≥12; own <12). Linear mixed effects models with subject-specific random intercepts and random slopes were stratified by race/ethnicity and tested for a 3-way interaction term (exposure x Latino x time). Models controlled for age, sex, place of birth and retest effects. Baseline verbal memory scores did not differ for first-generation compared to multi-generation high school graduates. Verbal memory decline was faster for first- compared to multi-generation high school graduates among non-Hispanic whites (e.g., β=-0.04; 95% CI: -0.05, -0.03, delayed verbal recall); among Latinos, first and multi-generation high school graduates had similar rates of decline (e.g. β=0.00; 95% CI: -0.03, 0.04, delayed verbal recall; p<0.001 for three-way interaction). Our findings suggest social and economic policies that facilitate educational achievement, particularly for important population subgroups, may reduce ADRD risk. Oxford University Press 2021-12-17 /pmc/articles/PMC8682417/ http://dx.doi.org/10.1093/geroni/igab046.3308 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Meza, Erika
Chen, Yea-Hung
Allen, Isabel
Gonzalez, Hector
Glymour, M Maria
Torres, Jacqueline
Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites
title Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites
title_full Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites
title_fullStr Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites
title_full_unstemmed Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites
title_short Intergenerational Education and Late-life Cognitive Decline among Latinos and Non-Hispanic Whites
title_sort intergenerational education and late-life cognitive decline among latinos and non-hispanic whites
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682417/
http://dx.doi.org/10.1093/geroni/igab046.3308
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