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Consequences of Genomic DNA Mono-Ribonucleotides for Chromosomal Stability

Mono-ribonucleotides are building blocks for polynucleotide RNA chains (e.g., messenger RNA), but if mis-incorporated into duplex DNA can cause mutagenesis and chromosomal instability. During DNA synthesis by Pol γ, remnants of unremoved RNA primers contribute to elevated mono-ribonucleotide triphos...

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Detalles Bibliográficos
Autor principal:	Roache, Tavia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682430/ http://dx.doi.org/10.1093/geroni/igab046.3574

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