Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants

BACKGROUND: Heterologous COVID-19 vaccination regimens combining vector- and mRNA-based vaccines are already administered, but data on solicited adverse reactions, immunological responses and elicited protection are limited. METHODS: To evaluate the reactogenicity and humoral as well as cellular imm...

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Detalles Bibliográficos
Autores principales: Groß, Rüdiger, Zanoni, Michelle, Seidel, Alina, Conzelmann, Carina, Gilg, Andrea, Krnavek, Daniela, Erdemci-Evin, Sümeyye, Mayer, Benjamin, Hoffmann, Markus, Pöhlmann, Stefan, Liu, Weimin, Hahn, Beatrice H., Beil, Alexandra, Kroschel, Joris, Jahrsdörfer, Bernd, Schrezenmeier, Hubert, Kirchhoff, Frank, Münch, Jan, Müller, Janis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682749/
https://www.ncbi.nlm.nih.gov/pubmed/34929493
http://dx.doi.org/10.1016/j.ebiom.2021.103761

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